II. INTRODUCTION
The diagnostic process has both medical and economic implications. Early diagnosis of …show more content…
This ratio is presented in a spectrum from which both elemental composition and concentration can be obtained.3 Mass spectrometry analysis offers several advantages due to its molecular selectivity and sensitivity.6 A common types mass spectrometry technique is Matrix-assisted laser desorption ionization imaging mass spectrometry (MALDI IMS).7 This method may incorporate either TOF (time of flight) or FT-ICR (fourier-transform ion cyclotron resonance) technologies depending on molecular compound weight. MALDI-TOF is typically used to analyze small proteins and peptides, whereas MALDI FT-ICR is characterized by high resolution and is often used for lower molecular weight