Once diagnosis is confirmed, treatment should be given right away. Back in the day, penicillin G in dosages of 10-24 million U/d was the drug of choice (Ho …show more content…
Nowadays, using both penicillin and clindamycin is widely used. According to the World Health Organization, they recommend taking Penicillin G and metronidazole for 5-7 days. For an adult, taking IV 1 – 5 MIU every 6 hours and after 2 days, you can take 2 Penicillin V tablets every 6 hours. While taking that, you also take IV 500 mg of Metronidazole every 8 hours which should be infused over 20 minutes. There are patients who are allergic to penicillin so they would just substitute it with a combination of clindamycin and metronidazole. But before antibiotics are given, they first drain the wound and remove infected tissues to prevent the spreading of infection (Carlisle 2014). The mechanism of action of the drug, penicillin G, is during active multiplication the synthesis of cell wall multiplication outcomes in bactericidal activity against susceptible