The affected infant will have a cat-like cry, being the main apparent symptom. If Cri Du Chat syndrome is suspected, an analysis of the chromosomes will be performed. The deletion of the short arm of chromosome five is the requirement for a positive Cri Du Chat syndrome diagnosis. Using the FISH analysis may be needed for further validation (Learning). FISH analysis translates to fluorescence in situ hybridization and is “used to visualize where a particular gene or DNA sequence is located within a person’s genome.”(Genetics Education) Also, Karyotype, a simple chromosome analysis, can be used to map out one’s chromosomes and make missing or added chromosomes apparent. Lastly, chromosome microarray analysis is the newest modern form of diagnosis which helps to analyze DNA by collecting and analyzing the affected individual's DNA and placing it on a glass slide, then comparing it to a control DNA which then makes mutations apparent. Furthermore, life expectancy can not be determined for those with Cri Du Chat syndrome. Many people affected by Cri Du Chat syndrome are able to lead happy, successful, and fulfilling lives
The affected infant will have a cat-like cry, being the main apparent symptom. If Cri Du Chat syndrome is suspected, an analysis of the chromosomes will be performed. The deletion of the short arm of chromosome five is the requirement for a positive Cri Du Chat syndrome diagnosis. Using the FISH analysis may be needed for further validation (Learning). FISH analysis translates to fluorescence in situ hybridization and is “used to visualize where a particular gene or DNA sequence is located within a person’s genome.”(Genetics Education) Also, Karyotype, a simple chromosome analysis, can be used to map out one’s chromosomes and make missing or added chromosomes apparent. Lastly, chromosome microarray analysis is the newest modern form of diagnosis which helps to analyze DNA by collecting and analyzing the affected individual's DNA and placing it on a glass slide, then comparing it to a control DNA which then makes mutations apparent. Furthermore, life expectancy can not be determined for those with Cri Du Chat syndrome. Many people affected by Cri Du Chat syndrome are able to lead happy, successful, and fulfilling lives