a) Cystic fibrosis affects ion transport in what type of cells? (1 mark) Cystic fibrosis affects ion transport in epithelial cells b) The CFTR protein regulates the transport of a number of ions; name 2 of these ions. (2 marks)…
Introduction The genetic autosomal recessive disorder known as Cystic Fibrosis (CF) effects on average 1 of 28 Caucasians. The average age for patients to be diagnosed with this genetic disorder is around 2 weeks and 2 years old, there are some cases where they are find out sooner and others when they are adults. CF affect the patient’s chloride channels which causes the mucus in their lungs to thicken and pool. It can also affect the pancreas by blocking it up and not allowing it to produce digestive enzymes.…
Website: http://www.wsvn.com/story/26299941/camps-take-cystic-fibrosis-patients-surfing Cystic fibrosis (CF) is a genetic-disease that causes thick, sticky mucus to build up in the lungs, digestive tract, and continues throughout other areas of the body. Cystic fibrosis has signs and symptoms that differs, depending on how bad the disease affects someone. Cystic fibrosis varies through ages, it affects infants, teenagers, and young adults, but is mostly found in white people.…
People who are prone to delta F508 mutation tend to have more critical symptoms of cystic fibrosis because of the lack of chloride ion transport, needed to control the thin layer of mucus that can be removed by the cilia lining the lungs and organs. The lack of chloride ion transport causes a thick mucus layer that the cilia can not remove, which in result traps bacteria causing disease. The chloride channels are to let chloride out of the epithelium cells. Someone who does that have cystic fibrosis the channels will open a fair amount of times in order to keep it balanced inside and outside of the cells,…
Since the discovery of the gene, doctors have been trying to to create effective therapies to treat Cystic Fibrosis. One of the doctors who works at the Sick Kids Hospital in Toronto, and studies the cystic fibrosis gene said, “Finding the gene opened the door to unprecedented knowledge of the disease. After its discovery we were able to study and understand how the protein made by the CFTR gene worked and what happened when it didn’t, Once we figured this out, therapy that targeted defects caused by CF gene mutations could begin” (Doctor Christine Bear). The discovery of the Cystic Fibrosis gene has helped the doctors learn much more about the disease and hopefully will help them find a cure to Cystic Fibrosis in the…
The anatomical changes that cystic fibrosis has on the endocrine system are poor growth development and delayed puberty in children. This condition affects the pancreas and its secretions. The pancreas is involved with secreting enzymes, that break down food, as well as the hormone insulin, which controls blood sugar levels. Cystic fibrosis causes these secretions to become thicker and pancreatic ducts become blocked.…
Cystic Fibrosis is an inherited disease of the secretory glands, glands that make up mucus and sweat. It is also known as mucoviscidosis, that affects mostly the lungs but also the pancreas, liver, kidneys and intestine. Long term issues include difficulty breathing and coughing up sputum as a result of frequent lung infections. A defect in the CFTR gene causes cystic fibrosis. This gene makes a protein that controls the movement of salt and water in and out of your body's cells.…
Cystic Fibrosis Presentation Cystic fibrosis is genetic disorder. It is an inherited disorder that can result in a severe damage to the respiratory and digestive systems. This disorder can affect the lungs, pancreas, intestines, liver and even the sex organs. Cystic fibrosis builds up a thick and sticky mucus in the lungs and other respiratory and digestive organs in our body. For an infant to be at risk of developing Cystic Fibrosis, both parents must pass on the abnormal gene to the infant.…
Cystic Fibrosis was first discovered in 1938 by Dr. Dorothy Hansine Andersen, she described the characteristics of the disease of the pancreas, lungs, and other organs, but this was not much information to go on from. She later discovered more information on Cystic Fibrosis in 1949, she found out it was caused by a recessive mutant gene. Cystic Fibrosis(CF) is a thick and sticky mucus that clogs the airways, making it hard to breathe and causing damage. It is caused by a defect in a gene that changes a specific protein that regulates the movement of salt in and out of cells at birth. In order for someone to be diagnosed with CF, the child would need to get one copy of the gene from both parents.…
Cystic Fibrosis are known to be a recessive disorder, meaning that both parents must a carrier of the gene in order to pass on the defective gene to any of their children in order to get the disease. If the faulty gene is inherited by one of the children, he or she will also be a carrier of the gene. Being a carrier of the disease will not affect the carrier, but the gene can be passed down to their children. This essay will address the biological basis and symptoms of Cystic Fibrosis, the treatments and/or management of this disease, and the issues, controversies regarding genetic screening. (University of Utah | Health Sciences, 2015) 1.…
Cystic Fibrosis is a genetic disorder that prevents how a person’s body make mucus and sweat. It also affects how a person’s lungs and digestive system works. Cystic Fibrosis causes mucus to become very thick, and sweat to be saltier than usual. Thick mucus can make it very hard to breath and can block pancreas, which will make it difficult to digest food properly. Offspring inherits this disease from their parents this illness is common among white people.…
CF is an autosomal recessive gene disorder caused by mutations in a pair of genes located on chromosome 7.1 There are thousands of combinations of gene mutations that can lead to a diagnosis of cystic fibrosis. These are referred to as cystic fibrosis transmembrane conductance regulator (CFTR).1 Cystic fibrosis affects about 30,000 children and adults in the United States, and about 70,000 worldwide per the Cystic Fibrosis Foundation.1 Cystic fibrosis does not just affect the respiratory system, it also encompasses other body systems. These include exocrine gland function, pancreas insufficiency, high chloride concentrations in the sweat, kidneys, liver, and intestines. Cystic fibrosis patients also have abnormalities in sodium and chloride production which aids in the dysfunction of the mucociliary transport…
Cystic fibrosis (CF) is a lifelong, hereditary disease that causes thick, sticky mucus to form in the airways, causing lung damage, making it hard to breathe, and leading to serious lung infections. In the pancreas, it clogs the pathway leading to the digestive system, interfering with proper…
Cystic Fibrosis is a life shortening disease which causes an abnormal collection of mucus in the lungs, pancreas, and other organs. “Mucus is a substance made by tissues that line some organs and body cavities, such as the lungs and nose. Normally, mucus is a slippery, watery substance. In victims of Cystic Fibrosis it becomes thick…
It is very common in our society with 1200 of the 70,000 affected worldwide living in Ireland (Cystic Fibrosis Ireland, 2014). CF causes the body to produce thick sticky mucus that blocks the lungs and causes lung infections. CF also stops the body for producing pancreatic enzymes which are necessary for breaking down and absorbing food. There are various symptoms of CF including, salty skin, persistent coughing often with phlegm, lung infections, shortness of breath, poor growth and weight gain and heavy stools or difficulty with bowel movements (Cystic Fibrosis Ireland, 2014). CF is caused by a gene that is passed from parent to child.…