Abstract
Background: Shivering is one of the most stressful complications for patient and surgeon during spinal anesthesia. In this prospective, randomized, double blinded study we compared the efficacy of Dexmedetomidine versus Granisetron for control of post spinal shivering.
Methods: study was conducted on 120 patients, ASA I-III, of either sex, aged 18–60 years, scheduled for elective lower abdominal and lower abdominal surgeries under spinal anesthesia. Response rate, time taken for control of shivering, recurrence rate, and adverse effects were recorded.
Results: From 1127 patients; 28 patients developed grade 4 shivering, and 92 patients developed grade 3. Heart rate and blood pressure were significantly lower in Dexmedetomidine group compared to Granisetron group during the 1st hour but no evidence of severe bradycardia. Shivering disappeared in 48 (96%) Dexmedetomidine and 46 (92%) Granisetron patients, rescue dose was given in …show more content…
2008).
To our knowledge, no study assessed Granisetron effect in management of post spinal shivering; thus we planned this study to assess Granisetron effect in control of post spinal shivering, and compare it with Dexmedetomidine. Hypothesis of this study was that each of Granisetron, and Dexmedetomidine when administered intravenously could control or decrease severity of post spinal shivering.
Aim: the aim of this study was to compare the efficacy and safety of Dexmedetomidine with that of Granisetron for control of shivering following spinal anesthesia.