Gene therapy is the process of supplementing or replacing a gene in order to treat a medical condition. This type of therapy allows the body to make the protein that is not being made by the missing or malfunctioning gene. Introduction of new genes through vectors overrides the malfunctioning gene and contributes to normal functioning of the body. The process begins when the modified DNA is inserted into a virus vector. Then, the vector binds to the cell membrane. After the vector binds to the cell membrane, a vesicle forms around the vector as it enters the cell. Thereafter, the vesicle breaks down, releasing the vector. Then, the vector inserts the DNA it contains into the cell’s nucleus. The cell makes a functional …show more content…
Normally cancer cells that make CD-47 escape the immune system, by turning off CD-47 the immune system was able to target cancer cells. Herpes virus was modified to not cause soars and injected in the body it bonded to cancer cells, which lead the cancer cells to die. It also attracted immune cells to help fight cancer. Treatment for cancer like chemo therapy, radiation treatment, and surgery have high risk of damaging body cells. Gene therapy is accurate and only affect cancer cells. Gene therapy has worked, for example a one-year-old girl named Layla was saved from aggressive leukaemia, after all other treatment options failed, thankfully gene therapy worked. On the other hand, gene therapy has unintentionally caused cancer in hundred of patients in clinical trials. After intense gene therapy a total of 2 patients have died as a direct result of gene treatment. Gene therapy also causes many other negative side effects for example:
Unwanted Immune system reaction = Since your immune is made to protect your body, it might possibly attack the newly viruses as intruders. This may cause inflammation, and some serve cases organ