[2] A study aimed to see if having knowledge of the influenza vaccine changed the likeliness of getting a flu shot was performed. It was found that the overall vaccination rate was low and that elderly and healthcare workers were more likely to get the influenza vaccine. Female gp actually had more vaccinated patients than their fellow male GPs. Prior to this …show more content…
We explored whether collective concerns about the safety, effectiveness, and necessity of influenza vaccines mediate racial/ethnic disparities in vaccine uptake among health care workers (HCWs). We used a self-administered Web-based survey to assess race/ ethnicity (exposure), concerns about influenza vaccination, and influenza vaccine uptake (outcome) for the 2012 to 2013 influenza season among HCWs at St. Jude Children's Research Hospital in Memphis, Tennessee. We used mediation analysis to estimate prevalence ratios (PRs) and 95% confidence intervals (CIs) for the total, direct, and indirect effects of race/ethnicity on influenza vaccine uptake.
Non-Hispanic Blacks had lower influenza vaccine uptake than non-Hispanic Whites, largely mediated by high concern about influenza vaccines. Hispanic and Asian HCWs had modestly lower uptake than non-Hispanic Whites, also mediated by high concern about influenza vaccines. Racial/ethnic disparities among HCWs could be attenuated if concerns about the safety, effectiveness, and necessity of influenza vaccines were reduced.
HCW= health care …show more content…
121XP stock derived by reverse genetics was more heterogeneous than X-179A and X-181 stocks prepared by conventional reassortant technology. Passaged 121XP virus contained four non-synonymous mutations in the HA gene. One of these mutations (Lys226Glu) was located in the Ca antigenic site of HA (present in 18% of the population). Two non-synonymous mutations were present in HA of viruses derived from X-179A: Pro314Gln (18%) and Asn146Asp (78%). The latter mutation located in the Sa antigenic site was also detected at a low level (11%) in the wild-type A/California/07/2009(H1N1) virus, and was present as a complete substitution in X-181 viruses derived from X-179A virus. In the passaged X-181 viruses, two mutations emerged in HA: a silent mutation A1398G (31%) in one batch and G756T (Glu252Asp, 47%) in another batch. The latter mutation was located in the conservative region of the antigenic site Ca. The protocol for RNA sequencing was found to be robust, reproducible, and suitable for monitoring genetic consistency of influenza vaccine seed stocks.
4. Influenza vaccine is an up and coming research field. The global trends of IVV area a multi developing feature of variety but an uneven technical research resource distribution. Even though the influenza vaccine is a relatively young field it already demonstrates the powerful vitality and the enormous development space. With the worldwide