Osteogenesis imperfecta (OI) is a genetic disorder that causes the bone to be fragile and break easily. It is also known as “brittle bone disease”. It is caused when there is a lack of collagen production. Collagen are what makes the bone strong, and the lack of collagen causes the bones to be weak and fragile, making it easier for it to break. OI affects 1 in 20,000 people. In the United States alone it is estimated to affect 20,000 at a minimum rate and 50,000 at the most. It can affect both male and female of any racial group. There are eight types of OI.
Symptoms of OI vary on the type. Some of the type I symptoms would be skin bruising easily, triangular shaped face, scoliosis, brittle teeth; sclera of the eye