point) Interpret A.S.’s laboratory test results and describe their significance to the patient’s disease process. Both the Hemoglobin and hematocrit are low which can be a sign of kidney failure. When the kidneys start to fail the amount of erythopoietin being relased c often times decreases and the erythopoietin is what stimulates the red bloos cell production. WBC’s are on the low side but still within normal range.…
This response results in a lack of oxygen binding to hemoglobin in the blood because red blood cells have a high affinity for binding to oxygen. Less oxygen to enter other cells will cause a decrease in energy leading to the symptoms that both Mark and Emily are experiencing. 2,3-DPG helps decrease the affinity of red blood cells with oxygen. Therefore, oxygen is able to distribute more throughout the body. Also, it will lower heart rate and help with rapid breathing and shortness of breath.…
OBJECTIVE #1 - The clinical manifestation of, and risk factors for, rhabdomyolysis • Rhabdomyolysis is a condition of skeletal muscle breakdown due to the release of intracellular components into the bloodstream, including myoglobin, creatine kinase, aldolase, lactate dehydrogenase, and electrolytes (DynaMed Plus, 2016). • The patient may experience systemic symptoms that may include fever, malaise, nausea, dyspepsia, emesis, muscle pain, weakness and swelling of injured muscles, tea-colored urine (DynaMed Plus, 2016). • High statin dosage and renal disease combined are associated with an increased risk for developing rhabdomyolysis (Wiley, 2006, p. 357). Other high risk factors include the use of drugs and/or alcohol, high body temperature,…
Biology 201 B1 Assignment #2 A four question analysis on "The myosin-interacting protein SMYD1 is essential for sarcomere organization" by Just et al. (2011) 1.) Wild-type Fla Mutant (SMYD-deficient) In the current study, the authors used a zebra fish mutant known as Flatline (fla). This mutant contains a nonsense mutation within the SMYD1 gene, consequently, these mutants show disturbed sarcomere assembly.…
During this process you also loss a good amount of iron along with hemoglobin. Her red blood cells are lower than normal which in turn effects the oxygen carrying capabilities. With decreased iron, the blood cannot carry oxygen efficiently throughout the body. 4. Interpret the results of Laura's bloodwork.…
Th e capacity of tissues to regulate their own blood fl ow is referred to as autoregulation. Most vascular beds have an intrinsic capacity to compensate for moderate changes in perfusion pressure by changes in vascular resistance, so that blood fl ow remains relatively constant. Th is capacity is well developed in the kidneys (see Chapter 37 ), but it has also been observed in the mesentery, skeletal muscle, brain, liver, and myocardium. It is probably due in part to the intrinsic contractile response of smooth muscle to stretch (myogenic theory of autoregulation). As the pressure rises, the blood vessels are distended and the vascular smooth muscle fi bers that surround the vessels contract.…
A muscle tear refers to muscle fibers being damage (Virginia 2013). A tear in the gastrocnemius can cause great risk of injury since the gastrocnemius is located between the knee and ankle joint (Virginia 2013). This can be cause by direct trauma to the calf region or sudden landing on the foot (Medial Head Gastrocnemius 2006). This injury is common in tennis players due to the constant motions of jumping and lunging (Medial Head Gastrocnemius 2006). In the first degree of gastrocnemius tear, the individual will experiment pain but the tendon will not be lengthened (Medial Head Gastrocnemius 2006).…
Raniel Gernale BIOL-130-02 Prof. Pericone Rigor Mortis Rigor mortis is a condition causing the body to stiffen several hours after death (Zhou, 2015). This occurs when both breathing and the heartbeat ceases to continue. Cells of the body will no longer receive their oxygen which in turn stops aerobic respiration. In the muscle, actin and myosin filaments cause the contractions until ATP binds to myosin and detaches the actin and myosin from each other.…
Rhabdomyolysis is “A possibly fatal condition in which skeletal muscle breaks down due to injury such as physical damage to the muscle, high fever, metabolic disorders, excessive exertion, convulsions or anoxia of the muscle for several hours, large amounts of myoglobin are usually excreted. ”(Huether & McCance, 2012, p. 1097) In acute renal failure myoglobin precipitates in the tubules obstructing the flow through the nephrons and causing injury. Damage to the myocyte causes an influx of sodium into the cell and cytosolic calcium accumulation due to direct injury to the cell. The high calcium concentration has a number of dangerous effects including the activation of phospholipase A2 which results in toxic metabolites and cell death.…
Troponins in ESRD Troponins in symptomatic patients with suspected ACS Elevation of troponin t is associated with adverse outcomes in symptomatic patients with suspected ACS, regardless of the degree of renal insufficiency [11]. Troponin t concentrations reach higher peaks and it remains detectable for longer time in patients with advanced renal failure. Repeated early measurements of troponin t are needed to detect a pronounced rise indicating an acute ischaemic episode, as patients with ESRD already have increased troponin irrespective of cardiac event. No protocols have been defined yet on frequency and intervals of blood sampling. Troponins in asymptomatic patients without suspicion of ACS…
Myotonic Muscular Dystrophy Research Paper Written By: Yaa Quaning Myotonic Muscular Dystrophy is a type of muscular dystrophy that affects muscles and certain organs in the body. MMD is part of a group of inherited disorders called muscular dystrophies. According to Genetic Home Reference,both types of MMD are inherited in an autosomal pattern. It was founded by a german doctor in 1909, stated by MDA.…
Hypospadias is a congenital anomaly with an incidence of 1/300 that is characterized by the opening of the external urethral meatus anywhere on the ventral surface of the penis other than its normal site at the tip of the glans penis (3). Hypospadias continues to be a challenging problem. The current operative concept in hypospadias surgery is based on a perfect single-stage repair of the malformation and should result in functional excellence and a cosmetically normal looking penis. A successful hypospadias repair includes a vertical slit-like glandular meatus, a conically shaped glans, a straight penis during erection, good skin coverage and a normal position of the scrotum in relation to the penis. These parameters reflect the expected…
Introduction By definition Rhabdomylosis is a rare disease that causes a breakdown of muscle tissue that releases a damaging protein into the blood. Fewer than 200,000 people are diagnosed in the United States yearly. Rhabdomylosis causes an excess level of myoglobin, which can and eventually will cause further injury. There are multiple causes of this disease such as trauma, nontraumatic exertional rhabdomyolysis, and other miscellaneous causes.…
What is Muscular Dystrophy? MD is a type of disease that is inherited, which causes a loss and wasting away of the skeletal muscles in one’s body. Currently, there are several types of MD. This research paper will focus on Myotonic Muscular Dystrophy. Myotonic Muscular Dystrophy is the most common form of MD that affects the muscles of the face, neck, and arms, has no treatment and has several ways to be diagnosed, and has a foundation that helps people who have the disease with medical situations and treatment.…
Aniline 1-MSDS: a) Handling: Must be Kept locked up, kept away from the heat and ignition sources. All equipment that contain the material should be grounded. Do not ingest or breathe the fumes, spray, gas, and vapor. Wearing the suitable protective clothing is important. In the case of improper ventilation, wear the adequate respiratory equipment.…