A typical example of such a case was illustrated by Lockie and Hubbard when they studied the effect of a high fat diet on patients with gout. They placed four gout patients whose symptoms had subsidies on a high fat low carbohydrate diet and they observed a prompt return of the symptoms, as well as by a reduction of uric acid output and a rise in blood uric acid. These patients were then put on a high carbohydrate low fat diet, which prompted a relief in symptoms. The factor responsible for the decrease in uric acid excretion in the urine of subjects on a high fat diet was concluded to not be the increased calorie intake but rather the high fat content itself. (D. Aldersberg,
A typical example of such a case was illustrated by Lockie and Hubbard when they studied the effect of a high fat diet on patients with gout. They placed four gout patients whose symptoms had subsidies on a high fat low carbohydrate diet and they observed a prompt return of the symptoms, as well as by a reduction of uric acid output and a rise in blood uric acid. These patients were then put on a high carbohydrate low fat diet, which prompted a relief in symptoms. The factor responsible for the decrease in uric acid excretion in the urine of subjects on a high fat diet was concluded to not be the increased calorie intake but rather the high fat content itself. (D. Aldersberg,