Transcranial magnetic stimulation (TMS) is a non-invasive method of brain stimulation that relies on electromagnetic induction using a magnet field over the scalp, focused on an area of the brain thought to play a role in mood regulation. The coil generates brief magnetic pulses, localized, which causes depolarization of neurons in underlying part of cerebral cortex which pass easily and painlessly through the skull and into the …show more content…
Studies showed the treatment was associated with a little rate of response and recognized many complications and side effects, which were significant and harmful, and reflect the need for more evolution and caution when using TSM (Durmaz et al,2015; Wassermann, 2000). Carpenter et al, (2012) indicated that the most universal side effect that were reported with patient who treated with TMS, headache after session, In addition ,about one third of patients experienced localized scalp pain sensations or facial twitching with TMS pulses. Indeed, TMS can stimulate seizures by its activating effect; this is considered to be serious side effect of TMS use ( Durmaz et al,2015) moreover, many studies indicated increase in thyroid-stimulating hormone (TSH) , release of dopamine , increase in glutamate/glutamine (Strafella et al. 2001; Padberg et al. 2002).Other study shown psychotic symptoms induced by TMS to the dorsolateral prefrontal cortex in patients with depression ( Zwanzger et