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9 Cards in this Set
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trypanosomiasis common name
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trypanosomiasis - African sleeping sickness (T. brucei) (2 strands: T.b. gambiense W. African & T.b. rhodesiense E. African)
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African Trypanosomiasis causal agent
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Trypanosoma brucei (2 strands: T.b. gambiense W. African & T.b. rhodesiense E. African) - Mastigophora (hemoflagellates) - Vector-borne - blood parasite
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African Trypanosomiasis reservoir & transmission
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zoonotic - vector-borne - human host - bite by tsetse fly - vector - T.b.g. in dense vegetation along rivers & forests - T.b.r in savanna woodlands & lakefront thickets
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African Trypanosomiasis portals of entry/exit - toxin -virulence factor - area affected
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nervous system - brain - heart - lymphatic system - many organs
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African Trypanosomiasis signs & symptoms
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intermittent fevers - enlarged spleen - swollen lymph - joint pain - cns becomes affected - personality + behavioral changes occur - lassitude - sleep disturbances - uncontrollable sleepiness during day - sleepless night - neurological deterioration signs are: muscle tremors - shuffling gait - slurred speech - seizures - local paralysis - death results from coma, secondary infection, heart damage
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African Trypanosomiasis lab id
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distinctive fly bite in endemic area - trypanosomes are readily demonstrated in blood & spinal fluids or lymph nodes -
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African Trypanosomiasis treatment
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chemotherapy - melarsoprol - suramin - eflornathine - pentamidine
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African Trypanosomiasis prevention
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applying insecticides - trapping flies - destroying shelter & breeding sites -
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African Trypanosomiasis other information
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n/a
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