- Shuffle
Toggle OnToggle Off
- Alphabetize
Toggle OnToggle Off
- Front First
Toggle OnToggle Off
- Both Sides
Toggle OnToggle Off
Front
How to study your flashcards.
Right/Left arrow keys: Navigate between flashcards.right arrow keyleft arrow key
Up/Down arrow keys: Flip the card between the front and back.down keyup key
H key: Show hint (3rd side).h key
PLAY BUTTON
PLAY BUTTON
32 Cards in this Set
- Front
- Back
|
Cholinergic drugs work on the ______ Nervous system
|
parasympathetic
|
|
______ (__) is the presynaptic and postsynaptic neurotransmitter in the Parasympathetic Nervous system
|
Acetylcholine (Ach)
|
|
Acetylcholine (Ach) is an ______ neurotransmitter that ____ HR
|
excitatory
increases |
|
Acetylcholine (Ach) is released in response to an _____ ____, diffuses across the synaptic cleft, and binds to _____ receptors on the target organs or tissues
|
action potential
cholinergic |
|
Activation of nicotonic receptors in the _____ _____ results in the release of epinephrine
|
adrenal medulla
|
|
Stimulation of nicotonic receptors results in ____ muscle contraction
|
skeletal
|
|
Direct acting muscarinic agonist prototype drug is?
|
*pilocarpine*
|
|
What is the antidote to pilocarpine?
|
*atropine*
|
|
Stimulation of the Muscarinic receptors results in the pharmacologic response of ______ resulting in ___ blood pressure
|
vasodilation
decreased |
|
What are the 3 groups of cholinergic agonists?
|
D.A. muscarinic agonists
D.A. nicotinic agonists I.A. cholinergic agonists |
|
The therapeutic uses of parasympathetic drugs are related to providing extra cholinergic _____ or _____ normal ANS functioning
|
stimulation
blocking |
|
The two significant classes of nicotinic stimulants are the ____ stimulants and the _____ nicotinic stimulants.
|
ganglionic
neuromuscular |
|
Direct-Acting Nicotinic Agonists prototype drug is...
|
Nicotine
|
|
Therapeutic value of Nicotine
|
Used as an ADJUNCT to smoking cessation programs
|
|
Nicotine most common adverse effects
|
erythema, pruritus, burning, headache, insomnia
|
|
Nicotine most serious adverse effects
|
vasculitis
|
|
Therapeutic value of Pilocarpine
|
Used for simple and acute glaucoma, preop and postop intraocular tension, mydriasis, and xerostoma
|
|
Pilocarpine most common adverse effects
|
blurred vision, myopia
|
|
Pilocarpine most serious adverse effects
|
cholinergic crisis, bronchospasm
|
|
Monotherapy use of nicotine replacement is the preferred treatment for smoking cessation. True or False?
|
False, nicotine replacement is considered an adjunct to smoking cessation
|
|
Cholinergic antagonists are drugs that antagonize, or block, _____ or _____ receptors directly
|
muscarinic
nicotinic |
|
Clinical importance of Cholinergic antagonists is?
|
*Increasing the Heart *
|
|
Cholinergic antagonists prototype drug
|
*atropine*
|
|
What is the therapeutic use for atropine?
|
Cardiac arrhythmias
|
|
atropine is a strong ____ of cholinergic receptors
|
inhibitor
|
|
Most common adverse effects of atropine
|
*blurred vision, dry mouth, constipation, and urinary retention*
|
|
Most serious adverse effects of atropine
|
*cardiac arrhythmias*
|
|
The PSNS stimulates the __ system and decreases ___ and ___ and ___ function to preserve energy
|
GI
metabolism, cardiovascular, respiratory |
|
In the PSNS, the transmitter is ___, and the receptors may be ____ or _____
|
acetylcholine
muscarinic or nicotinic |
|
Acetylcholine is inactivated by ________
|
Acetylcholinesterase
|
|
A prototype I.A. cholinergic receptor stimulant is ____, which is used to control the symptoms of ____ _____.
|
neostigmine
myasthenia gravis |
|
Atropine is most commonly used...
|
preop to dry post op secretions
|
