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23 Cards in this Set
- Front
- Back
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What does Skeletal muscle use preferentially in fasting states?
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Fatty acids.
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Gluconeogenesis makes glucose from what substrates?
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Lactic acid ( DUHHH), glyercol ( ehhh), alpha-ketoacids (wtf)
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What happens in deficiency state of Vitamin A?
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Night blindness, Skin disorders, Resorption of fetus, Growth retardation, Loss of taste.
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What is the most toxic vitamin and what does it do at toxic level?
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It is vitamin D and it will deposits Ca2+ in arteries and kidneys and very high doses increases cancer risk.
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What vitamin can cause microcytic anemia upon deficiency?
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Vitamin B6 booyahhh pyridoxine or pyridoxal.
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Which vitamin deficiency causes seborrheic dermatitis?
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Biotin, it would take 20 raw egg white ingestion to cause binding up of the biotin.
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What activates Phosphofructokinase 1?
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Insulin, AMP, and Fructose 2,6-P (which is made when there is excess fructose-6-p back up).
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Where is glucose 6- phosphatase found for gluconeogenesis?
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Liver and kidney.
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What is the effect of steroids on glycolytic pathway?
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It actually has an affect on gluconeogenesis causing hyperglycemia.
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How does acyl CoA produce Acetyl CoA for TCA cycle?
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Beta oxidation.
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Purines/Pyrimidines excess inhibits what part of synthesis?
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Going from Ribose-5-PO4 to Phosphoribosyl pryophoshate (PRPP)
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ATP production overview simple?
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Glycolysis to Krebs cycle to ETC
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Pryuvate to Acetyl CoA is a decarboxylation....what enzyme does this?
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Pyruvate DH
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How many ATP's are yielded from ETC from breakdown of NADH and FADH2 for one glucose?
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34 ATP
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Acetyl CoA and NADH, and ATP inhibits what?
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Pryuvate DH from taking Pyruvate to Acetyl CoA
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Which hormone increases liver gluconeogenesis and glycogenesisi?
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Coritsol
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What is the anticodon?
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3 adjacent nucleotides in tRNA that pair, in the opposite direction, with the mRNA codon (3'-5').
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Which type of RNA is involved with the structure of ribosome?
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rRNA
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Which mRNA is polycistronic meaning that it can encode for multiple proteins. Verse the opposite which can only code for one protein?
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Prokaryotic mRNA
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What inhibits RNA polymerase II (eukaryotic)?
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Alpha-amanitin( remember, a potent toxin from poison mushrooms and toadstools).
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What brings exons into correct alignment for splicing?
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Introns are excised and this happens with the help of small ribonucleoprotein particles (snRNPs) which are made from Polymerase II
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What is the function of Single stranded binding protein in DNA replication?
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It keeps the single strand from re-annealing works after helicase.
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What is the major DNA polymerase in bacteria?
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It is polymerase 3----copies both parental strands, and only reads and copies parental strands in 3' to 5' direction. and has proofreading ability and 3' exonuclease activity to remove wrong nucleotides.
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