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215 Cards in this Set

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What is Copaxone? Dose?
Glatiramer (for Multiple Sclerosis)
20mg SC QD
Storage for Copaxone?
Fridge
Room temperature, good for 1 month
What is Avonex? What's another brand name?
Interferon beta-1A
Rebif
What is the dosing difference between Avonex and Rebif?
Avonex - 30mcg IM Qweek
Rebif - 8.8-44mcg SC 3x week
Storage for Interferon beta 1A?
Refrigerate
Good for 30 days @ RT except for the Avonex prefilled syringe which is good for 7 days.
Other names for Interferon beta-1B
Betaseron
Extavia
Storage for Interferon beta-1B
Room temperature until reconstitute, then refrigerate and use within 3 days
What is Tysabril?
Natalizumab, for Multiple Sclerosis
Who are given Tysabril?
Multiple Sclerosis patients who are enrolled in a program; patient and prescriber needs to be enrolled in a program bec the medicine causes brain infection.
Dosing for Tysabril?
300mg IV infusion over 1H Q4 weeks
Monitoring parameters when using Interferons
#1 Symptom: Flu - like symptoms

CBC
CV disease
Depression
Seizure
Suicidal ideation
Thyroid function
What's the diagnostic test for Cystic Fibrosis?
Sweat Gland Chloride test
What is cystic fibrosis also known as?
Mucoviscidosis
What should you avoid when taking Pancreatic enzymes?
Calcium carbonate
Magnesium hydroxide
What is Nebcin? Other brands?
Tobramycin, used to prevent pseudomona infections in Cystic Fibrosis.
TOBI (another brand name)
Dosing for TOBI?
300mg (nebulizer soln) BID 28 days on, 28 days off
What are the Aztreonam nebulizers used for CF?
Cayston - 75mg INH TID 28 days on, 28 days off
Azli
Dosing for Cayston?
5mg TID (via Altera Nebulizer System), 28 days on & 28 days off
Storage for Cayston?
Fridge
Room temperature, okay for 28 days
What are the mucolytics used in Cystic Fibrosis?
Acetylcysteine (Mucomyst)
Pulmozyme (DNAse alpha)
Mucomyst nebulization dose?
3-5mL of 20% solution TID-QID, diluted with NaCl or sterile water
Storage for Pulmozyme?
Refrigerate
Protect from light
What allergy should you look out for when using Cayston?
Beta-lactam allergy
First line meds for glaucoma?
Beta blockers
What is Betoptic?
Betaxolol
Important patient counseling on Betoptic S?
Shake well before use
1-2 gtts BID
What is Ocupress?
Carteolol
What is Betagan?
Levobunolol
What is Timoptic?
Timolol
What is the strength of Betoptic S?
0.25% suspension
Shake!!!!
What is Travoprost? Dose?
Travatan
QHS
What is Bimatoprost?
Lumigan
Latisse
What is Latanoprost? Dose?
Xalatan
QHS
Storage for Travatan?
Refrigerate unopened
Room temperature, discard after 6 weeks
Storage for Xalatan?
Refrigerate unopened
Room temperature: open, discard after 6 weeks.
Patient counseling on the use of Latisse?
Apply QHS to the upper eyelid margin at the base of the eyelashes
What is Alphagan P?
Brimonidine, alpha adrenergic
What should you not use with Alphagan P?
MAO inhibitor
What is Cosopt?
Dorzolamide - Timolol
What is Combigan?
Brimonidine - Timolol
What is Azopt?
Brinzolamide 1% susp
Patient counseling on Azopt?
Suspension. Shake well!!!!!
What is Trusopt?
Dorzolamide
Dosing for Azopt?
1 gtt TID
Dosing on Trusopt?
1 gtt TID
Trusopt strength?
2% solution
What is Diamox? Regular dosing? ER dosing?
Acetazolamide

Dose: 350mg PO QID

ER: 500mg BID
Diamox dosing for acute glaucoma?
500mg IV
What is Neptazane? Dose?
Methazolamide is given 100mg Q12H
What should you look out for when using Carbonic Anhydrase Inhibitors?
Sulfa allergy
What are the brand names for Naphazoline/Pheniramine?
***VON

Visine-A
Opcon-A
Naphcon-A
Patient counseling on the use of Naphazoline/Pheniramine (2)?
Remove contact lenses, to avoid accumulation of the preservative benzalkonium chloride
Should not be used >3 days.
Naphazoline/Pheniramine is contraindicated with (4)?
***GEHH


Glaucoma
Enlarged prostate
Heart disease
HTN
What is Emadine? Strength? Dose?
Emedastine 0.05% is a pure antihistamine given QID
What is Elestat? Strength? Dose?
Epinastine 0.05%
BID
What is Zaditor? Strength?
Ketotifen 0.025% (OTC)
What is Olopatadine? Strength? Dose?
Pataday 0.2% - QD
Patanol 0.1% - BID
What is Optivar? Strength? Dose?
Azelastine 0.05%
BID
Other names for Levofloxacin eye drops? Strength?
Iquix 1.5%
Quixin 0.5%
What is Zymar? Strength? Dose?
Gatifloxacin 0.3% soln
1-2 gtts Q2H x 2days, then 1-2 gtts Q4H x 5days
Brands for Moxifloxacin eye drops? Indication? Strength? Dose?
Vigamox, approved for >1 yr old, is a 0.5% soln given 1 gtt TID x 7 days.

Moxeza, approved for >4 mos, is also a 0.5% soln given 1 gtt BID x 7 days.
What is Besifloxacin? Strength? Dose?
Besivance 0.6% soln

SUSPENSION!!!!

1 gtt TID x 7 days
What is AzaSite? Dose? Storage?
Azithromycin

1 gtt Q12H x 2 days, then 1 gtt x 5 days

Fridge, discard after 14 days
What is Xerophthalmia?
Dry eyes
What are the two medications used for Hyperthyroidism? Dosing?
Methimazole (Tapazole), given WITH FOOD

Propylthiouracil (PTU), given TID
What do you monitor when on Hyperthyroidism medications?
Pregnancy Cat D
WBC - b/c it causes agranulocytosis
LFT's
TSH - hepatitis
Monitoring parameters when treating Hyperthyroidism
WBC (bec of agranulocytosis)
LFT's
TSH
Can you use propranolol for hyperthyroidism?
Yes; it provides symptomatic relief by blocking conversion of T4 to active T3
Can you use Diltiazem for hyperthyroidism?
Yes, it is an alternative to using B-blockers
Can you use Cholestyramine for hyperthyroidism?
Yes, it increases fecal excretion of T4
What is Armour thyroid?
Dessicated (pig) thyroid which provides both T3 & T4
Brands for Levothyroxine
Levoxyl
Synthroid
Levothryoid
Half-life of Levothyroxine? What is the equivalence ratio of PO to IV? Storage? Points to remember when making IV soln?
Half-life: 7 days

PO to IV: 1/2 of the PO dose

Storage: Room temperature

Dilution: 5mL Normal saline, shake well and use immediately
What is Triostat? Other name?
Liothyronine, synthetic pure T3
Cytomel
What is Thyrolar?
Liotrex, synthetic T3 & T4
What is Zyban?
Bupropion SR 150mg
What is Chantix?
Varenicline
Dosage for Nicorette?
***OTC
<25 cigs/d: 2mg gum
>25 cigs/d: 4mg gum
1 gum Q1-2H x 6 wks then 1 gum Q2-4H x 3 wks then 1 gum Q4-8H x 3 weeks
Other names for the Nicotine patch? Dose?
NicoDerm CQ
Habitrol
-worn for 24H or 16H to avoid insomia/vivid dreams

Dose: If >10 cigs/day, then 21mg/24H x 4 wks (6wks for Nicorderm CQ), then 14mg/24H x 2 wks, then 7mg/24H x 2 wks
What is Nicotrol NS? Max dose?
nasal spray, 1 dose = 2 sprays
Max: 40 doses/day
Nicotrol comes in what form? Hold old must the client be to purchase nicotine products?
Inhaler
Nasal spray

***FDA prohibits sale of nicotine products to individuals <16 YO.
Dosing for Zyban?
150mg QAM x 3 days then BID
Dosing for Chantix?
0.5mg QD x 3 days then 0.5mg BID x 3 days then 1mg BID
- PC with a full glass of water to avoid nausea
What are the caution/contraindication for using Chantix?
Renal (CrCl<30mL/min)
Psychiatric disorders
Driving/operating machinery
Nicotinic receptors activation causes insomia
How often do you change Fentanyl patch?
Q3 days (72H)
What is the ratio of Morphine IV to Oral?
1:3
IV = 10
PO = 30
Equivalent dose of Morphine to Fentanyl patch?
Morphine 45mg = Fentanyl 12.5
What is Opana?
Oxymorphone
Morphine comes in what forms?
Tabs
Elixir
IV/SC/IM
suppositories
Name 2 morphine antagonists?
Naloxone (Narcan)
Nalmefene (Revex)
Where is morphine metabolized? Major SE?
Morphine is metabolized in the liver and excreted with active metabolized by the kidneys.

SE: CNS, constipation, vasodilation, histamine release (itching), respiratory depression
Which morphine brand can you crush?
MSIR (immediate release tabs)
Which morphine brand can be opened and sprinkled on food?
Avinza ER
Kadian CR
What is Embeda? Dosing? Why can't you use it with alcohol?
Morphine - Naltrexone, ER; around the clock dosing for chronic, moderate to severe pain

Dose: QD/BID, can be opened and sprinkled on food

Caution: alcohol speeds up the release of morphine which can lead to respiratory depression
What is Lorcet?
Hydrocodone - APAP
10/650 tabs
What is Percodan? What schedule does it belong?
Oxycodone - Aspirin
Control II
Brands for Oxycodone - APAP
Roxicet
Percocet
What do you need to avoid when using Oxycodone?
Inhibitors (its a substrate), bec it can cause respiratory depression
Brand names for Methadone?
Diskets
Dolophine
Methadose
Dosing for Methadone?
Severe pain: 5 & 10 mg
Opioid dependence: 40 mg
What can you give to patients allergic to morphine?
Methadone
Meperidine, Sufentanil, Fentanyl, or Remifentanil
What are the different brands of Fentanyl products?
INJECTION: IM/IV Sublimaze

LOZENGES: for cancer patients, ACTIQ

IR TABS: Abstral, NEW!!!!! REMS required

PATCH: Duragesic

BUCCAL - tabs: FENTORA; film: ONSOLIS
Name 4 Opoiod Agonists with their brand names
Hydromorphone (Dilaudid: IM/SC/IV) (Exalgo ER: OROS tabs)

Meperidine (Demerol, Pethidine)

Oxycodone (Roxicodone, Oxycontin, Percolone) (3A4 substrate)

Oxymorphone (Opana)
What are the different forms of Morphine?
IR tabs - MSIR

CR - Ms Contin & Oramorph; don't break or chew!!!!

Caps - Avinza ER & Kadian CR, can be opened and sprinkled on applesauce

Solution: Roxanol

Suppository: RMS
What is Stadol?
Butorphanol
What is Dilaudid?
hydromorphone
What is Nubain?
Nalbuphine
Wha tis Subutex?
Buprenorphine
What is Suboxone?
Buprenorphine - Naloxone
Max dose for Tramadol?
400mg/day
300mg/day for >75 yo
Can you use Tramadol for renal patients (CrCl<30mL/min)?
Yes, but max dose is 200mg/day
Who can use Utram ER?
>18 yo
List the medications for urinary incontinence
Oxybutinin (Ditropan)
Trospium (Sanctura)
Darifenacin (Enablex)
Solifenacin (Vesicare)
Fesoterodin (Toviaz)
Tolterodine (Detrol)
What do you monitor when using Azulfidine?
CBC
LFT's
CNS
What is Dipentum?
Olsalazine
What is Colazal?
Balsalazide
What is Ambien?
Zolpidem
What is Sonata?
Zaleplon, good for early night awakening. 3A4 substrate
What is Lunesta?
Eszopiclone, longest half life. Keeps you asleep
What is Rozerem? Dose?
Ramelteon
8mg QHS, 30 min before sleeping
Accutane is approved for use by patients over what age?
>12 yo
Accutane dosing?
0.5 - 1 mg/kg/day divided BID
SE of Accutane?
cheilitis
Sun sensitivity
Psych
Hepatotoxicity
CBC
What is Elidel?
Pimecrolimus (Elidel) 1% cream
What is Protopic?
Tracrolimus (Protopic)
What is Abreva? Dose?
Docosanol (OTC) is a cream for facial herpes

Dose: 5x/day for 10 days >12 YO
What is Denavir? Equivalent to what OTC medication?
Pencyclovir 1% (Rx), a cream for cold sores, is equivalent to Abreva.
What is Aldara?
Imiquimod 5% cream for genital herpes
What is Tacrolimus?
Prograf, 3A4 substrate
What is Rapamune?
Sirolimus, Rapamycin
3A4 Substrate
Other names for Cyclosporine?
Sandimmune
Neoral
Gengraf
-3A4 substrate
What is CellCept? How do you take it?
Mycophenolate taken on EMPTY STOMACH
What is Ditropan?
Oxybutinin
What is Enablex?
Darifenacin
What is Vesicare?
Solifenacin
What is Toviaz?
Fesoterodin
What is Detrol?
Tolterodine
What is Sanctura?
Trospium
What are the oral agents for Erectile Dysfunction?
***All are substrates

Sildenafil (Viagra, Revatio - 20mg TID)

Tadalafil (Cialis, Adcirca - 40mg QD)

Vardenafil (Levitra)
Trade names for Mycophenolate mofetil?
Cellcept

Myfrotic
MoA for Alprostadil? Brands? Dosing?
Alprostadil is a PGE-1 that works by widening blood vessels, increase flow to the penis and helps cause erection.

Muse - pellet inserted into the penis. No more than BID. Fridge; RT: 14days

Caverject - injected; not to be used >3x/week. Room Temperature!
Monitoring parameters when using CellCept?
***PIC

Pregnancy test (prior to initiation due to risk of malformations & abortions)

Infections: signs & symptoms

CBC
What is Butrans? MoA? Schedule? Dose?
Buprenorphine patch

MoA: partial opioid agonist and antagonist

Schedule: III, once-a-week patch
What is Vivitrol? Dose?
Naltrexon ER helps patients stay off opioids after detox.

Dose: once a month IM injection
MoA of Nucynta? Indication?
Nucynta (Tapentadol)

MoA: Opioid agonist & NE reuptake inhibitor

Indication: moderate to severe acute pain >18 yo
SE for Nucynta?
Respiratory depression

CNS depression

Increased risk in seizure and serotonin syndrome
What is Ofirmev?
Acetaminophen IV for patients weighing >50kg
What are the two Inflammatory Bowel Diseases?
Ulcerative Colitis - blood in the stool due to ulcerations

Crohn's Disease - no blood in the stool, only inflammation
Management of Ulcerative Colitis
Salicylates
Corticosteroids: oral, then rectal
Immunosupressants
List the brand names for Mesalamine
***L-CRAP

Lealda: QD
Canasa: rectal suppository
Rowasa: rectal suspension
Asacol: 400mg DR
Pentasa: CR caps, QID
Monitoring parameters for Azulfidine use?
Azulfidine (Sulfasalazine)

Monitor: LFT's, CBC, CNS
What is IBS?
Iriitable Bowel Syndrome involves abdominal pain & abnormal bowel movements.
What is the first line of treatment for diarrhea?
Imodium (Loperamide)
What is Lotronex? Who can prescribe this medication?
Lotronex (Alosetron) is a 5-HT3 antagonist for patients who've failed Imodium.

Prescribers must be enrolled in the Prescribing Program for Lotronex (PPL) and the prescription must have a PPL sticker before it can be filled.
Treatment for diarrhea in IBS
Calcium supplements
Decrease coffee, alcohol, spicy foods and sweeteners.
Lotronex (Alosetron) (Rx)
Imodium
Treatment for constipation in IBS?
Mg supplements
Amitiza (Lubiprostone) (DoC)
Zelnorm (Tegaserod maleate)
What is Amitiza?
Amitiza (Lubiprostone)

Dose: 24mcg BID (Chronic Idiopathic Constipation in adults)
8mcg BID for IBS
Causes of lung infections in Cystic Fibrosis patients
Pseudomona aeruginosa
Haemophilus influenza
Staph aureus (MSSA, MRSA)
Brukholeria cepacia
ABPA (Allergic Broncho Pulmonary Aspergillosis)
MAC
Early symptoms of Cystic Fibrosis
Failure to gain weight
No bowel movement in the first 24-48H
Salty tasting skin
Pale, foul smelling stools with mucus
Recurrent episodes of pneumonia
List the medications used for Multiple sclerosis
Gilenya (fingolimod caps)
Glatiramer (Copaxone)
Interferon beta-1A (Avonex, Rebif)
I terferon beta-1B (Betaseron, Extavia)
Natalizumab (Tysabri)
Dosing for Gilenya? Monitor what?
Gilenya (Fingolimod) - Multiple sclerosis

Dose: 0.5mg caps PO

Observe for 6H for S/Sx of bradycardia.
List the Equivalent dosing for Steroids
Cortisone 25mg
Hydrocortisone 20mg
Methylprednisolone 4mg
Triamcinolone 4mg
Prednisolone 5mg
Prednisone 5mg
Dexamethasone 0.75mg
What are the tests for Sickle Cell Disease?
CBC
Hemoglobin electrophoresis
Sickle cell test
What age does the symptoms for Sickle Cell Disease start to show?
>4 months
Patients with Asplenia should be vaccinated with?
Pneumococcal vaccine - Prevnar PLUS Pneumovax
Hib
Annual influenza
Meningococcal vaccine - >2 YO
Sickle Cell Disease measures
PCN prophylaxis
Vaccinations
Hydroxyurea
Folic Acid: 1mg QD
Malaria Chemoprophylaxis
Bone marrow or stem cell transplants
What can you give as PCN prophylaxis to Sickle Cell Disease patients less than 5 YO?
PVK 125mg BID

PCN allergy: Erythromycin
Brand names for Hydroxyurea? MoA? Monitor?
Brands: Hydrea & Droxia

Monitor: CBC

MoA: reactivates fetal hemoglobin production instead of hemoglobin S.
How do you give Zovirax IV? Storage?
Slow IV infusion over at least an hour.
Refrigerate.
What do you reconstitute Zovirax with? Solutions for infusion?
Reconstitution: Sterile water
Infusion: D5W, NS, LR
What Cephalosporins are okay to use in renal patients?
Cefoperazone
Ceftriaxone (Rocephin)
What is Ancef? Storage?
Cefazolin
Fridge: 10 days
What is Ceftriaxone? Storage?
Rocephin
Fridge: 10 days
What is Cefobid? Storage?
Cefoperazone
Fridge: 5 days
What is Cefotan? Storage?
Cefotetan
Fridge: 4 days
What is Fortaz? Storage?
Ceftazidime
Fridge: 7 days
What is Maxipime? Storage?
Cefepime
Fridge: 7 days
What is Mefoxin? Storage?
Cefoxitin
Fridge: 7 days
What is Zinacef? Storage?
Cefuroxime
Fridge: 7 days
What is the max dose for Rocephin?
4 grams IM injection (with 1% lidocaine)
What should never be mixed with Rocephin?
Calcium
Storage for Ciprofloxacin IV powder?
Room temperature
Storage for premixed Levofloxacin?
Room temperature
Storage for diluted levofloxacin?
RT: 72H
Fridge: 14 days
Freezer: 6 months
Storage for Vancomycin?
RT: 24H
Fridge: 14 days
What can you mix Bactrim with? Storage?
D5W
DON'T REFRIGERATE
RT: 6H
What is the usual IV Bactrim dosing?
8 - 10mg/kg/day div 2x, 3x, 4x/d
IV Bactrim dose for PCP?
15-20mg/kg/day in divided doses
What is the Bactrim dose for renal patients?
CrCl 15-30mL/min
- 50% of usual dose Q12H
What do you dilute Flagyl IV with? How is it given?
Normal Saline, given as slow IV drip infusion
What do you dilute Rifampin with?
D5W - stable for 4H @ RT
NS - stable for 24H
Storage for IV Diltiazem?
Refrigerate, DON'T freeze
Room Temperature - 1 month
Indications for Octreotide?
Acromegaly
Diarrhea
Sandostatin dosing?
Diarrhea: 100-600mcg/day SC/IV

Sandostatin LR: IM Q4W x 2
What is Anectine?
Succinylcholine
What is Diprivan?
Propofol
List some OTC meds that can cause bleeding (3G's & DEFF)
Ginger, Garlic, Ginko
Dong Quai
Vit. E
Fever Few
Fish Oil
Black Cohosh is used for?
Menopausal symptoms
Everning primrose oil is used for?
Eczema; but it decreases seizure threshold
What is Fever few used for?
Migraine prophylaxis
Glucosamine-Chondroitin is contraindicated in what allergy?
Shellfish
Dosing for ferrous sulfate?
Iron Deficiency Anemia: 325 TID
Hgb 7- 9 325 TID
Hgb 9-10 325 BID
Hgb >10 325 QD
Iron SE?
Constipation
Diarrhea (when given too much)
Black stool
APAP dose for well-hydrated children? Dehydrated? Max dose?
well-hydrated: 15mg/kg Q4-6H
dehydrated: 10mg/kg Q4-6H
Max: 90mg/kg/day
What is Acetadote?
IV form of acetylcysteine
Dose of NAC?
1st dose: 140mg/kg
Following doses: 70mg/kg Q4H x 17 doses
What should be given for Aspirin toxicity?
Sodium Bicarbonate, to increase pH of urine which results to aspirin elimination
What is Anaprox?
Naproxen sodium 550mg Q12H
What is Zostrix?
Capsaicin, AAA 3-5x QD
What is Qutenza? Dosing?
Capsaicin patch, may be repeated Q3 months; apply within 4H or opening pkg.
What is Tessalon Perles?
Benzonatate, 100-200mg TID
What is Hycotuss? Schedule?
Control III
Hydromorphone-Guaifenesin
What is Hycodan? Schedule?
Hydrocodone - Homatropin
Control III
What is Lomotil?
Diphenoxylate - Atropine
What is Imodium? Dosing? Max?
Loperamide
Initial: 4mg PO
Titrate: 2mg PO after each loose stool
Max: 16mg/day; OTC: 8mg/day