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What are trade names for acetaminophen?
Tylenol, Tempra, Panadol, Robigesic, Atasol
What are examples of prescription products with acetaminophen?
Darvocet-N 100, Lortab, Percocet, Vicodin
What is acetaminophen used for? What is it not used for?
It relieves muscular aches and pain, headache and fever. It is not used for any inflammatory process.
What are examples of OTC products with acetaminophen?
Actified: Cold and Allergy, Sinus; Anacin; Excedrin; Goody's Powders' Midol: Maximum Strength Menstrual Formula; Percogesic; Vicks
What are contraindications?
Severe hepatic or renal disease, alcoholism, hypersensitivity
What is the advantage of acetaminophen over salycylates and NSAIDs?
It causes little to no gastric distress and does not interfere with platelet aggregation.
What is the frequency of administration and the maximum dose per day? What is an exception?
Every 4hrs as needed with a maximum dose of 4g/day.
Clients who frequently takes acetaminophen should limit the dose to 2g/day to avoid hepatic or renal dysfunction.
When large doeses are administered over a long time, what must be monitored and what are the norms?
The therapeutic serum range is 5-20mcg/ml. Liver enzyme levels (aspartate aminotransferase [AST], alanine aminotransferate [ALT], alkaline phosphatase [ALP] and serum bilirubin should be monitored.

The toxic level is >50mcg/ml. >200mcg/ml could indicate hepatotoxicity.
What are the side effects and adverse reactions of acetaminophen?
An overdose can cause hepatotoxicity. Early symptoms of hepatic damage include nausea, vomiting, diarrhea, and abdominal pain.
What are Drug-Lab-Food Interactions?
Increase effect with caffeine, diflunisal
Decrease effect with oral contraceptives, anticholinergics, cholestyramine, charcoal