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19 Cards in this Set

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  • Back
What is viral translation?
Virus makes the proteins necressary for the capsid
What is semi-conservative DNA replication?
How most DNA viruses replicate ,except the pox virus, using the parent strand template.
What is segmented DNA?
DNA like the influenza virus can break up into different segments, in order to Reassort and give new properties
What is negative RNA?
Normal RNA that needs to make + mRNA to make proteins
What is positive RNA?
RNA that can use itself to make proteins and does not need to transcribe mRNA
What type of RNA does Hep B have?
Partial dsRNA
Where is the sickle cell mutation?
x11, Glu6Val
What 3 things do viral mutations result from?
1. Base substitution
2. Frame shift
3. Transposons
What are the viral markers HA and NA?
HA = hemaglutanin
NA = Neuramidase
What is complementation?
Having two sets of viruses produce complementary proteins
What are psuedotypes?(2)
1. DNA of one virus is put into the capsid of another virus
2. phenotypic mixing
What is a lytic infection(3), what types of viruses use this?
1.Non enveloped viruses
2. Replicate in cells
3. lyse the cells to get out
What is a latent infection?
1. Having an infected cell that is healthy until activated later
What is a persistant infection?
1. Continuous replication, as the host cell remains viable
What is viral transformation?(2)
1. Virus transforms the host genome to produce viral products
2. Host cell becomes cancerous
How do viruses attach to the cell?(2)
1. Glyco, single or mosaics of proteins
2. Fibers (adenovirus)
How does a virus penetrate into a cell?
1.After attachment its coat fuses with the cell membrane
Virus in an endosome?
1. Low pH causes uncoating and the viral genome is released in the cytoplasm or the nucleus
How and where does the synthetic phase(replication) of an RNA or DNA virus take place?(2)
1. RNA viruses replicate in the cytoplasm, except the flu and RT viruses
2. DNA viruses replicate in the nucleus except POX