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19 Cards in this Set
- Front
- Back
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What is viral translation?
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Virus makes the proteins necressary for the capsid
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What is semi-conservative DNA replication?
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How most DNA viruses replicate ,except the pox virus, using the parent strand template.
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What is segmented DNA?
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DNA like the influenza virus can break up into different segments, in order to Reassort and give new properties
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What is negative RNA?
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Normal RNA that needs to make + mRNA to make proteins
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What is positive RNA?
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RNA that can use itself to make proteins and does not need to transcribe mRNA
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What type of RNA does Hep B have?
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Partial dsRNA
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Where is the sickle cell mutation?
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x11, Glu6Val
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What 3 things do viral mutations result from?
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1. Base substitution
2. Frame shift 3. Transposons |
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What are the viral markers HA and NA?
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HA = hemaglutanin
NA = Neuramidase |
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What is complementation?
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Having two sets of viruses produce complementary proteins
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What are psuedotypes?(2)
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1. DNA of one virus is put into the capsid of another virus
2. phenotypic mixing |
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What is a lytic infection(3), what types of viruses use this?
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1.Non enveloped viruses
2. Replicate in cells 3. lyse the cells to get out |
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What is a latent infection?
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1. Having an infected cell that is healthy until activated later
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What is a persistant infection?
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1. Continuous replication, as the host cell remains viable
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What is viral transformation?(2)
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1. Virus transforms the host genome to produce viral products
2. Host cell becomes cancerous |
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How do viruses attach to the cell?(2)
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1. Glyco, single or mosaics of proteins
2. Fibers (adenovirus) |
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How does a virus penetrate into a cell?
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1.After attachment its coat fuses with the cell membrane
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Virus in an endosome?
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1. Low pH causes uncoating and the viral genome is released in the cytoplasm or the nucleus
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How and where does the synthetic phase(replication) of an RNA or DNA virus take place?(2)
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1. RNA viruses replicate in the cytoplasm, except the flu and RT viruses
2. DNA viruses replicate in the nucleus except POX |