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8 Cards in this Set
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- Back
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What is comventionally day 1 of mensturation?
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The first day of bleeding
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Describe the proliferative stage of the menstural cycle
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- Early part
- Under the influence of oestradiol from the developing preovulatory follicle - The endometrium grows from 0.5 mm to 3-5 mm - The endometrial glands are narrow and tubular while the stroma becomes progressively less dense |
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What triggers the secretory phase of the endometrium?
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Following ovulation at day 14, the ovary secretes large amounts of progesterone as well as the oestradiol. The endometrium then ceases proliferation and enters the secretory phase
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Describe the secretory stage of the menstural cycle
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- The endometrial glands become progressively more tortuous and dilated as secretion of the glycogen rich mucus begins
- The supporting stromal cells become larger and increasingly oedematous |
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What happens to the endometrium if pregnancy does not occur?
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The decline in progesterone initiates a:
- Shrinking endometrium - Spiral arterioles supplying the endometrium spasm causing ischaemia and stasis - Influx of inflammatory WBC initiating the release of prostaglandins - Tissue collapses leading to bleeding and shedding of the spongiosum layer of the endometrium |
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How much blood is lots during mensturation?
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Average: 30mL
Range: 10 to 80mL |
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Why doesn't normal menstural blood clot?
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Because of the presence of fibrinolytic substances
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What 3 factors limit menstural blood loss?
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- Partial occlusion of the spiral arteries with platelet and fibrin plugs
- Predominance of F series prostaglandins (vasoconstrictors) over E series (vasodilators) - Ovarian follicle growth supplying oestrogen to regenerate the endometrium |
