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8 Cards in this Set
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- Back
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What is the composition of the crystals associated with gout?
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Monosodium urate
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What are the two aspects of the appearance of crystals under plane-polarized light?
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Yellow
Negatively birefringent |
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Where do articular erosions generally appear in patients with gout?
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Generally away from the joint surface itself
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What is the drug of choice to inhibit associated inflammatory mediators?
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Colchicine
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What two drugs act to inhibit phagocytosis?
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Phenylbutazone
lndomethacin |
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What is the mechanism of action of allopurinol? When it is indicated?
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Xanthine oxidase inhibition
For chronic gout suppression |
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What is the relationship between myeioproliferative syndrome (MPS) and gout?
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Chemotherapy for MPS may precipitate an attack of gout
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What are live potential causes of chondrocalcinosis?
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Calcium pyrophosphate deposition disease (CPPD, positively birefringent crystals)
Ochronosis Hyperparathyroidism Hypothyroidism Hemoch romatosis (primarily affects small joints) |
