adrenal glands Flash Cards

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Title: adrenal glands
Description: komar
Number of Cards: 29
Save Count: 0
Author: ttagami15
Created: 2012-01-23
Tags: endo
Private No

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    • Question
    • Answer
    • Side 3
    • layer of adrenal cortex that produces mineralocorticoids
    • glomerulosa
    • layer of adrenal cortex that produces glucocorticoids
    • fasciculata
    • layer of adrenal cortex that produces androgens
    • reticularis
    • produces catecholamines
    • adrenal medulla
    • regulators of the zona glomerulosa
    • ang II
      K
    • regulators of the zona fasciculata
    • ACTH
    • effects of ACTH on the zona fasciculata
    • increase in StAR
      (+) glucocorticoids
    • effect of ACTH on the pituitary
    • (-) CRH receptor
      (-) ACTH
    • effect of ACTH on the hypothalamus
    • (-) CRH
    • primarily found in the cytosol bound to heat shock proteins
    • glucocorticoid receptors
    • inhibits StAR and therefore glucocorticoid synthesis
    • ANP
    • ACTH binds to what receptor
    • melanocortin-2 receptor
    • inhibit ACTH release from the anterior pituitary
    • GC
    • secretion of mineralocorticoids is stimulated by what
    • Ang II
      extracellular K+ (increase)
      (ACTH)
    • secretion of mineralocorticoids is inhibited by what
    • ANP
    • example of glucocorticoid
    • cortisol
    • example of mineralocorticoid
    • aldosterone
    • converts active cortisol into inactive cortisol
    • 11beta-hydroxysteroid dehydrogenase (11BHSD)
    • where is 11BHSD located
    • kidney (reserves activation of GR for aldosterone by inactivating cortisol)
    • effects of mineralocorticoids (aldosterone)
    • (+) Na
      (-) K
    • adrenal androgens are important for what sex
    • females (males use testes)
    • cells that synthesize catecholamines in the adrenal medulla
    • chromaffin cells
    • primary products of chromafin cells
    • EPI (NE)
    • catecholamines (EPI/NE) are stored bound to what proteins
    • chromogranins
    • synthesis of EPI
    • tyrosine
      dopa
      dopamine
      NE
      EPI
    • ACTH effects on catecholamine synthesis
    • increase
    • cortisol effects on catecholamines
    • increase
    • 2 components of chromogranins (EPI/NE storage proteins)
    • vasostatin
      catestatin
    • clinical use of chromogranins
    • tumor eval