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10 Cards in this Set

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Name 3 short acting glucocorticoids.
Hydrocortisone
Cortisone
Fludrocortisone (this is also considered a minercorticoid, probably more so)
Name 4 intermediate acting glucocorticoids.
Prednisone
Prednisolone
Methylprednisolone
Triamcinolone
Name 2 long acting glucocorticoids.
Betamethasone
Dexamethasone
Pregnant woman comes in, and is having a planned premature delivery tomorrow. What adrenocorticoid could you give her to help the baby develop lungs?
Betamethasone (preferred)
Dexamethasone
What adrenocorticoid is commonly used for diagnosis of Cushing's syndrome/disease?
Dexamethasone

(Given low dose at first, and high dose later if indicated to help diagnose the specific pathology underlying Cushing's syndrome)
A person comes in with "Respiratory distress syndrome," what glucocorticoids could you use?
(Long acting)
Betamethasone
Dexamethasone
If you need to give a patient steroids, but the patient has hepatic insufficiency, what would you use?
Prednisolone because it's the active form.

(Not prednisone, because it's the prodrug (inactive) and it needs to be converted to prednisolone in the liver, so in this case it wouldn't work because of the liver insufficiency)

The liver enzyme repsonsible is "11 beta-hydroxysteroid dehydrogenase, it converts cortisone and prednisone to their active forms.
Pt comes in with Status Asthmaticus. What combo of drugs would you give (classes), and then fill in with specific examples of those classes.
Beta 2 agonist + steroid
Albuterol/Salmeterol + Hydrocortisone
List as many Adverse Effects of glucocorticoids that you can.
NOTE: these mainly seen when given at pharmacological doses, not when used as replacement therapy.

1. HPA (hypothalamus-pituitary-axis) suppression.
2. Cushing syndrome.
3. Osteoporosis
4. Peptic Ulcer
5. Oral candidiasis (inhalational)
6. Psychosis and Depression
7. Hypertension
8. Diabetes Mellitus
Triamcinolone is used to treat what?
Can be inhaled for Tx of asthma.
Keloid + RA