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233 Cards in this Set

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What are the functions of the Lymphatic System?
1. Drain excess interstital(tissue) fluid, filters it, and returns it to the circulatory system.
2. Transport dietary lipids(fats) from intestines to blood.
3.Carries out immune responses.
Lymph
what interstitial fluid is called once it enters the lymphatic system.
Edema
swelling (happens when to much interstital fluid accumilates in the tissue)
What are some treatments for edema?
1. Diuretics
2. Fluid Restriction
3. Bedrest
What are some causes of edema
1. Blackage in the lymphatic system
2. Removal of lymph nodes
3. Interstital fluid forms faster than it can drainaway
4. CHF (conjestive heart failure)
Lymphatic Capillaries
-Smallest lymph vessels
-One end lies in the tissue to collect fluid
-Other end is connected to lymphatic vessel
Lymphatic Vessels
-Have thinner walls & more valves than veins
Lymph Nodes
- Bean- shaped organs, found in groups
Where are large groups of lymph nodes located?
1. Mammary glands
2. Axillae (armpit)
3. Inguinal (groin)
What is the function of a lymph node?
-filter lymph, and carry out immune responses
What contains lymphocytes (T-cells, B-cells) & macrophages which are involved in immune responses?
Lymph Nodes
Lymph Truncks
-vessels at exits of lymph nodes
Ducts
- collect & return lymph to circulatory system at subclavian veins
Thoracic Duct
- main collecting duct; collects lymph from bottom half & upper left side of the body
Lymphatic Duct
- collects lymph from upper right side of the body only
Lymph Flow
Fluid collected by lymphatic capillaries-> lymphatic vessels->lymph nodes-> lymph trunks-> Thoracic duct or right lymphatic duct-> subclavian veins
What are some lymphatic organs?
- red bone marrow, thymus, spleen, lymph nodes
Red Bone Marrow
- produces lymphocytes (B & T cells); B cells mature here
Thymus
- T cells (fight infection) mature here
What is large in infants and starts to atrophy after puberty?
Thymus
Where is the spleen located?
- near the stomach on the left side
What is the spleen compsed of?
- white pulp (lymphatic tissue)
-red pulp (filled with blood)
What are the functions of the spleen?
- white pulp -immune responses(destroys invaders)
- red pulp -destroys old blood cells; stores platelets
Splenectomy
- surgical removal of the spleen
Lymphatic Nodules
- also carry out immune responses
-scattered throughout the mucous membrane (MALT)
MALT
-mucous associated lymphatic tissue
How many tonsils do we have?
- One pharyngeal tonsil (or adenoid)
- Two palatine tonsils
- Two lingual tonsils
Tonsillectomy
- surgical removal of the tonsils
Metastasize
- to spread
lymphoma
- cancer of the lymph nodes
Pulmonology
- study of the lungs
What are the functions of the respiratory system?
- Performs gas exchange (take in O2, eliminates CO2)
-Helps regulate blood pH
-Smell
-Speech
Upper respiratory system
-nose & pharynx (throat)
Lower respiratory system
- larynx, trachea, bronchi, & lungs
External nose
- part you see; made of cartilage & bone, lined with mucus membrane & hairs
External nares
- (nostrils)- openings where air enters & exits
Nasal cavity
- space inside nose
What is the nasal cavity composed of?
- palate, nasal septum, nasal conchae, internal nares
Palate
- floor of nasal cavity & roof of mouth
Nasal septum
-separates nose into right & left nostrils
Nasal conchae
- scroll- shaped bones that project into cavity; increase surface area inside nose
Internal nares
- openings between nasal cavity & pharynx
What are the functions of the nose?
- warming, moistening, and filtering incoming air
- smell
-modifies speech vibrations
Pharynx
throat
What are the functions of the pharynx?
- passageway for air and food
- modifies speech vibrations
- contains tonsils
What are the 3 regions of the pharynx?
- nasopharynx
- oropharynx
- laryngopharynx
Nasopharynx
- (superior)- lies behind the nasal cavity
Oropharynx
-(middle)-lies behind the oral cavity, contains other pairs of tonsils
Laryngopharynx
-(inferior)- common area before esophagus & larynx
Larynx
- voice box
Thyroid cartilage
- anterior wall of larynx, triangular- shaped, larger in men
Cricoid cartilage
- ring of cartilage below throid cartilage
Epiglottis
- cartilage flap that closes on top of larynx when you swallow (preventing food & liquid from getting into respiratory tract)
Where is the glottis located?
- inside the larynx
Glottis
- contains vocal cords/folds with a hole between for air to enter respiratory tract
Do males or females have loger thicker vocal cords that vibrate slowly?
-males-(results in a deeper voice)
True vocal cords
- muscles tighten the cords, then air passes over the cords causing them to vibrate, vibrations produce sound
Laryngitis
-inflammation of the larynx, vocal cords swell & can't vibrate
Trachea
- windpipe
- has C-shaped rings made of cartilage to reinforce trachea walls so they don't collapse
-lined with mucous membrane & cilla
What is the function of the trachea?
- tubular passageway for air; anterior to esophagus
What are 2 emergency airways?
- tracheotomy
- intubation
Tracheotomy
- opening made below cricoid cartilage
Intubation
- tube inserted into trachea, connected to ventilator
The Bronchial Tree
- primary bronchi-> secondary bronchi->tertiary bronchi-> bronchioles->terminal bronchioles
Primary bronchi
- first division, enters the lungs
Secondary bronchi
- subdivision, one branch enters each lobe of lung
Tertiary bronchi
- smaller branches
Bronchiloes
- even smaller branches
Terminal bronchioles
- end bronchiole, connected to alveoli(which performs gas exchange)
Layers of the airway
- mucosa->submucosa-> hyaline cartilage-> adventitia
Mucosa
- mucous membrane lined with with ciliated epithelium
Submucosa
- layer of elastic fibers & smooth muscle
Hyaline cartilage
- to keep airway open
Adventitia
- connective tissue
As airway brances the amount of smooth muscle_______ & amount of catilage _______.
- increases, decreases
Asthma
- chronic airwa yinflammation
- An allergic reaction which causes bronchi & bronchioles to spasm & constrict
What are some symptoms of asthma?
- difficulty breathing
- wheezing
- couphing
- chest tightness
Lungs
- pair of organs in the thoracic cavity
Pleual membrane
-2 layers that surround & protect each lung
Parietal pleura
- lines wall of thoracic cavity
Visceral pleura
- covers each lung
Pleural cavity
- space between membranes which contains pleural fluid (reduces friction between membranes)
Pleuritis
- inflammation of the pleual membrane
Pneumothorax
- air gets into pleural cavity, may cause lung collapse
How many lobes does each lung have?
- right lung has 3 lobes
- left lung as 2 lobes
Alveoli
- (air sacs)- surrounded by blood capillaries; main site of gas exchange in lungs
Surfactant
- fluid that prevents alveoli from collapsing
Macrophages
- also present to remove debris from air we breathe in
How does gas exchange happen?
- by diffusion across alveolar & capillary membranes
Pulmonary ventilation
- (breathing)- moving air into & out of the lungs
Inspiration/Inhilation
- air flows into lungs
Expiration/Exhalation
- air flows out of lungs
External respiration
- gas exchange between alveoli (lungs) & blood capillaries
Internal respiration
- gas exchange between the blood capillaries & the cells
Mechanics of breathing
- air will always move from an area of high pressure to an area of lower pressure
Diaphram
- dome- shaped skeletal muscle at floof of thoracic cavity; used in breathing
Eupnea
- normal breathing
Apnea
- temporary cessation of breathing
Dyspnea
- difficult breathing
Typical respiration rate
- 12-20 breaths per minute
Respirometer/Spirometer
- intrument used to measure breathing volumes (amout of air)
What variables affect lung capacity?
- height, gender, age, smoking, lung disease
Tidal volume (500 mL)
- amount of air in one normal breathe
Inspiratory reserve volume (3100 mL)
- amount of extra air that can be forcibly inhaled ( a deep breathe)
Expiratory reserve volume (1200 mL)
- amount of extra air that can be forcibly exhaled( after a normal exhalation)
Residual volume (1200mL)
- amount of air that always remains in lungs
Viral capacity (4800mL)
- TV+ IRV+ ERV
How does gas exchange happen?
- diffusion
Almost all oxygen is carried by ______ (inside RBCs)
- hemoglobin
Carbon monoxide poisoning
- hemoglobin prefers Co, which drastically reduces O2 levels in the blood, leading to hypoxia (O2 deficiency)
How is carbon dioxide transpoted in the blood?
- dissolved in blood plasme
- carried by hemoglobin
- majority is converted to bicarbonate ions
What controls respiration?
- areas in the medulla oblongata & pons
- we have some voluntary control
COPD
(Chronic obstructive pulmonary disease)
- respiratory disorder with chronic obstruction of airflow
What causes COPD?
- obstruction of airflow
- 2 as common in men
What are 2 types of COPD?
- Chronic bronchitis
- Emphysema
Chronic bronchitis
- chronic inflammation of the bronchi, excessive mucus is produced
Emphysema
- alveoli get destroyed, less oxygen can be exchanged
Lung cancer
- leading cause of cancer death in US
- 85% of lung cancer is related to smoking
- seconhand smoke causes lung cancer in nonsmokers
Pneumonia
- infection of the alveoli, can be viral/ bacterial
Tuberculosis (TB)
- highly contagious bacterial disease
Cystic fibrosis
- inherited disease that causes excess mucus production in the lungs (and other secretory epithelial tissues) & eventually causes lung disease
SIDS (sudden infant death syndrome)
- death of infant to 12 months of age due to hypoxia
Gastroenterology
- study of the stomach & intestines
Gastrointesinal (GI) tract
- continuous tube from mouth to anus
Peristalsis
- wavelike muscular contractions that move food along th GI tract
Accessory structures
- assist with digestion or produce chemicals needed for chemical digestion
What are the accessory structures in the digestive system?
- teeth, tongue, salivary glands, liver, gallbladder, & pancreas
Ingestion
- eating/ taking in food
Digestion
- food breakdown
Mechanical digestion
- chewing, cutting, grinding & churning food to break it into small pieces
Chemical digestion
- enzymes break food down into smaller molecules
Absorbtion
- movement of food from GI tract into blood / lymph
Defecation
- elimination of wastes & undigested material as feces
Steps of digestion
1. Ingestion
2. Digestion
3. Absorbtion
4. Defecation
What are the layers of the GI tract?
- Mucosa(mucus membrane )
-Submucosa
-Muscularis(2 to 3 layers of smooth musclewhich perform peristalsis)
-Serosa (AKA visceral peritoneum)
Peritoneum
- a serous membrane
What are the two layers of the peritoneum?
- parietal peritoneum
- visceral peritoneum
Parietal peritoneum
- lines wall of the abdominopelvic cavity
Visceral peritoneum
- covers organs in the abdominopelvic cavity
Peritoneal cavity
- space between the two peritoneum layers, filled with peritoneal fluid
Peritonitis
- an acute inflammation of the peritoneum, can be life-threatening
What are the boundaries of the mouth (oral cavity)?
- cheeks, hard & soft palates, tongue, oropharynx
Roof of mouth
- hard palate(made of bone) & soft palate (made of muscle)
What is the function of the salivary glands?
- secrete saliva
What is the function of saliva?
- moistens food,
-starts starch digestion
-washes mouth & teeth
What are the 3 pairs of salivary glands?
- parotid glands(in cheek, front of ear)
- submandibular blands(below mandible)
-lingual glands(below tongue)
What is the functions of the tongue?
- moves food around
- swallowing
- speech
- taste
Surface of the tongue contains ______ papillae wwhich have ______ .
-papillae, taste buds
What is the function of teeth?
-bite, chew, & grind food
Where are the teeth located?
- sockets of mandible & maxillae, surrounded by gums (gingivae)
What are the componets of the teeth?
-crown (visible portion of the tooth)
-roots(portion embedded in socket)
Tooth composition
-enamel(hard outer covering of crown)
-dentin(hard substance tooth is made of)
-Pulp & root canals(contain nerves & blood vessels
Dentition (sets of teeth)
- Primary or baby teeth
- Permanent teeth
a. incisors for biting
b. canines for tearing
c. premolars for grinding
d. molars for grinding
Where does digestion begin?
- mastication (chewing)
Composition of saliva
- mostly water
- mucus
- salivary amylase
Salivary amylase
- initiates the breakdown of starch
Pharynx
- throat
What is the function of the pharynx?
- swallowing (deglutition)
Bolus
- lump of chewed food that is swallowed
Esophagus
- collapsible, muscular tube
What is the function of the esophagus?
- moves food from the pharynx to stomach using peristalsis
Upper esophageal sphincter
- esophagus entrance
Lower esophageal sphincter
- (cardiac sphincter) - located between esophagus & stomach; relaxes to let food enter stomach
GERD ( Gastroesophageal Reflux disease)
- lower esophageal (cardiac) sphincter doesn't close properly; acidic contents of the stomach back up into esophagus; causes burning sensation of heartburn
Stomach
- J- shaped organ on the left side
Rugae
- large folds inside stomach (when it's empty); stretch & disappear when stomach is full
Pyloric sphincter
- connects stomach to duodenum
What are the functions of the stomach?
- mashes and mixes food
- temporarily stores food
- secreates gastric juice
- starts protein & fat digestion
Digestion in the stomach
- mechanical digestion
What is the composition of gastric juice?
- mucus- protects stomach lining
Hydrochloric acid (HCI)
- kills bacteria
- denatures (unfolds) proteins
- helps convert pepsinogen (inactive form) into pepsin (active form)
Pepsin
- enzyme which breaks down proteins
What is needed for vitamin B12 absorption?
- Intrinsic factor
Chyme
-liquid mixture of partially digested food & gastric juice
- slowly released from stomach into duodenum
Vomiting (emesis)
- forceful expulsion of stomach contents through the mouth
Pancreas
- organ located behind the stomach
Pancreatic islets
(islet of Langerhans)
- secrete insulin & glucagon (endocrine)
Acini
- secrete pancreatic juice
What stimulates the production of pancreatic juice?
- presence of chyme in duodenum which is then added to the duodenum
What is pancreatic juice composed of?
- Water
- Sodium bicarbonate (neutralizes stomach acid)
-Many digestive enzymes
Pancreatic enzymes
- pancreatic amylase (digest starch)
-pancreatic lipase (digest lipids)
-several enzymes which digest proteins
-Nucleases(digest nucleic acids)
Liver
- large, dark organ on right side (under ribs)
How many lobes does the liver have?
-2 lobes made up of many lobules
What does a lobule consist of?
-many hepatocytes arranged aroun a central vein. Kupffer's cells are also present
Kupffer's cells
-phagocytosis
Hepatocytes
-perform most liver functions, including bile secreation
What are the functions of the liver?
-metabolism of carbohydrates, lipids, & proteins
-breaks down drugs, alcohol, & hormones
-Produces bile
-storage of glycogen and some vitamins & minerals
-phagocytosis of old blood cells & bacteria
What is the function of bile?
-bile salts (in bile) emulsify (break apart) lipid globules
- once produced it leaves liver via the hepatic ducts
Gallbladder
-small sac located inderneath liver
What is the function of the gallbladder?
-stores bile
How does bile enter & leave the gallbladder?
-via the cystic ducts
Gallstones
-can block hepatic, cystic, or common bile ducts which blocks flow of bile
What are some treatments for gallstones?
-drugs, lithotripsy(shock-wave therapy), & surgery
Small Intestine
- long, coiled, partially- contracted hollow tube
What are the functions of the small intestine?
-chemical digestion & absorbtion of food
- chyme is moved through the intestines by peristalsis
What are the three regions of the small intestines?
-duodenum, jejunum. & ileum
Ileocecal sphincter
-connects ileum to large intestine
What are some structures that greatly increase the surface area inside the small intestine for nutrient absorbtion?
-circular folds
-villi( finger-like projections)
-microvilli(smaller projections on a villus)
Chemical digestion in the small intestine
-Carbohydrates are brocken down into disaccharides and then into monosaccharides
-Proteins are brocken down into peptides and then into amino acids
-Triglycerides(fats) are brocken down into glycerol & fatty acids
Small intestin absorbtion
-absorbs a lot of water
-Fats & fat-soluble vitamins are absorbed by lacteals
-All other nutrients are absorbed by blood capillaries
Large intestine (colon)
-puckered hollow tube that is larger in diameter than small intestine; millions of bacteria live inside
What are the functions of the large intestine?
-produce some vitamins
-finish absorbtion of water &vitamins
-form & eliminate feces
Cecum
- blind pouch of large intestin
Appendix
- attached to cecum
Appendicitis
- inflammation of the appendix
- can cause life-threatening peritonitis if it bursts
Colon
- asending, transverse, desendin & sigmoid regions
Rectum
- stimulates defecation reflex
Hemorroids
- varicose veins of the rectum
Anus
- opening through which feces are eliminated
Internal anal sphincter
- involuntary control
External anal sphincter
- voluntary control
Diarrhea
- increased motility of colon & decreased water absorbtion by colon
Result:frequent watery feces
Causes:illness lactose intolerance, stress, food poisoning
Constipation
- decreased mtility of colon & increased water absorbtion by colon
Result:infrequent, dry , hard, feces that are hard to pass
Causes:insufficient fiber, of fluids in diet, strees, lack of exercise
Jaundice
-yellowish color to the skin caused by a buildup of bilirubin, can indicate liver disease
Hepatitis
- inflammation of the liver caused by viruses, drugs, or alcohol
Hepatitis A
- spread by fecal contamination, mild
Hepatitis B
- spread by sexual contact or contaminated blood, can cause cirrhosis or liver cancer; vaccine to prevent it
Hepatitis C
- similar to hep b ( but no vaccine)
Peptic ulcers
- craterlike lesions (sores) that develop in GI tract; can cause bleeding
What are some causes of peptic ulcers?
- bacteria
- NSAIDs( esp asprin)
-Overproduction of HCI
Cirrhosis
- scarring of the liver
- caused by: hepatitis, drugs, alcoholism
Irritable bowl syndrome (IBS)
- pain and alternating bouts of diarreha & constipationw due to stress
Inflammatory bowl disease (Crohn's disease is one)
- inflammation of any part of the GI tract
Colorectal cancer
- begins as polyps ( small growths) on inside of colon
- genetics play a role
- Prevention: high-fiber, low-fat diet
What are some signs of colorectal cancer?
- constipation, diarrha, blood in stool, rectal bleeding & abdominal pain or cramping
Why do we need food?
- for energy
- serve as building blocks
-store energy for future use
Metabolism
- all chemical reactions that occur in the body
Catabolism
- breakdown reactions (release energy)
Anabolism
- synthesis reaction (stores energy, builds/repairs things)
Nutrients
- substances the body uses for energy, growth, maintenance, & repair of tissues
What are some Nutrients in the body?
-Carbohydrates, lipids, water, proteins, vitamins(organic nutriens required in small amounts) & minerals(inorganic elements)
Fat-soluble vitamins
- can be stored (A, D, E, K)
Water-soluble vitamins
- can't be stored (B, C)