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16 Cards in this Set
- Front
- Back
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Name the two classes of Antacids
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systemic and non-systemic
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what are the non-systemic antacids?
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calcium based
aluminum based Magnesium based |
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Name the systemic antacid
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Sodium based (bicarbonate)
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what is the MOA of antacids?
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the antacid binds to the hydrogen ions in the stomach and neutralizes them
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What should be present in higher quantities after the implementation of an antacid?
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Water
CO2 chloride salts |
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What is a common positive side effect to the LES after an antacid dose?
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increased tone
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What happens to pepsin activity and gastric acid secretion after the use of an antacid?
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pepsin activity decreases as pH increase
Antacids DONT have an effect on gastric secretion or production *could elicit a rebound effect* |
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What is the ANC and which antacid has the best/worst?
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ANC measures the neutralization ability of the antacid and is a measure of potency
Calcium has the best ANC and Aluminum has the worst clinically |
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a patient needs a slow onset antacid so the doctor prescribes?
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Aluminum hydroxide
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After swallowing this antacid, it contacts gastric acid. The antacid converts to Mg hydroxide and Al hydroxide. What is this antacid?
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Magaldrate
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Patient has been experiencing flatulence issues and expresses her need for antacid. what is the best choice?
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Simethicone
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Electrolyte workup of a patient reveals hypercalcemia. What antacid would a KCUMB grad avoid?
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Calcium
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A patient enters your office needing antacid. The patient complains that she has been constipated lately and has been "gassy." What is the best choice of antacid.
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Magnesium
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Patient comes in with reflux. charts reveal that he is hyperphosphatemic and has suffered from kidney stones in the past. What is the drug of choice?
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Aluminum
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Patient complains of both constipation and diarrhea when switching between antacids. What is a possible way to alleviate these side effects?
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combination of aluminum and Mg
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A heavily medicated women is being prescribed antacid. What would a KCUMB grad be thinking as far as pharmacology goes?
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take the antacid 1-2 hours before other meds or 2-4 hours after other meds
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