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33 Cards in this Set

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this ____ is a factor that affects the outcome of antibiotic therapy & is when/where bacteria mutate when exposed to antibiotics for extended periods of time
acquired resistance
this is a way co-administration of other meds can affect the propensity of antibiotic to work
the propensity to work is decreased b/c the other meds might decrease the absorption of the antibiotic
this is the biggest challenge to antibiotic therapy
stopping the therapy b/f the end of the course of meds - therefore one has not taken the meds long enough to ensure eradication of the infection
this is where peak levels are too high
direct toxicity
need peak/trough levels to prevent this from happening (generally)
direct toxicity
this type of infection is cz'd by antibiotic use
secondary infection
this type of infection is when a "bug" overgrows or mutates because of exposure to antibiotics
super infection
to prevent the most common secondary infection of candida overgrowth, educ. Ct's to eat this
yogurt and/or buttermilk, which will help keep normal flora levels up
these side effects are common for all antibiotic therapies
N/V & diarrhea
this med frequently causes an anaphaltic response
PCN
the generation of these drugs only refers to their response to gram +/- rods
cephalosporins
this catagory of drugs were found on fungi in sea water at a sewage treatmt. plant
cephalosporins
these are semi-synthetic derivativves of a fungus
cephalosporins
the spectrum (broad/narrow) of these drugs depends on what?
cephalosporins
this generation has good gm + coverage
cephalosporins - 1st
this generation of cephalosporins are traditionally used for surgical prophylaxis
1st
the 3 meds that are 1st generation of cephalosporins that are admin'd IV/IM are:
Cefazolin
Ancef
Kefzol
the 3 meds that are 1st gen. of cephs that are admin'd PO are:
Cephalexin
Keflex
Keftab
this generation of cephs have good gm +/- coverage
2nd
this generation of cephs are appropriate for treatment of anerobes
2nd
this generation of cephs are truly broad spectrum
2nd
the best available oral ceph against gm-'s is:
3rd gen - cefixime (Suprax)
this is the only 3rd generation ceph w/ an oral route
cefixime (Suprax)
this generation of cephs has good gm- coverage, but only some gm+ cvrg.
3rd
this 3rd gen of cephs can be given qDay via IM/IV
ceftriaxone (Rocephin)
this ceph is considered the "big guns" & easily passes the meniges and diffuses into CSF
ceftriaxone (Rocephin)
this 3rd gen ceph is highly protein bound
ceftriaxone (Rocephin)
this ceph is used for diseases that have propensity to go into one's CSF
ceftriaxone (Rocephin)
these anti-infectives have excellent oral absorption
quinolones
antacids reduce these anti-infectives absorption
quinolones
these are used to treat UTIs
quinolones
this was the first oral class of antibiotics that killed gm-
quinolones
you should alert your Ct's when they are receiving this class of meds to photosensitivity
quinolones