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17 Cards in this Set

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What is the MOA of Ethosuximide?
Ca
What is the MOA of Valproic acid?
Na
What is the MOA of Oxcarbazepine?
Na
What is the MOA of Carbamazepine?
Na
What is the MOA of Phenytoin?
Na
What is the MOA of Phenobarbital?
GABA
What is the MOA of Lorazepam?
GABA
What is the MOA of Diazepam?
GABA
What is the MOA of Levetiracetam?
binds to synaptic vesicle protein SV2A thereby modulating neurotransmitter release.
What is the drug of choice for neonatal seizures?
phenobarbital
What is the drug of choice for intantile spasms?
ACTH
What is the drug of choice for absence seizures?
valproic acid or ethosuximide
What is the drug of choice for generalized tonic-clonic seizures?
valproic acid, lamotrigine
What is the drug of choice for partial seizures (all types)?
oxcarbazepine, carbamazepine
What is the drug of choice for various seizure types?
levetiracetam
What three AEDs produce the most in the way of drug interactions because they induce CYTp450 enzymes and thereby enhance the metabolism or other medications
phenobarbital, phenytoin and carbamazepine
What AED is an enzyme inhibitor of the enzyme that metabolizes lamotrigine?
When this AED is given, how should the dose of lamotrigine be adjusted?
valproic acid.

Decrease the dose!