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24 Cards in this Set
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- Back
- 3rd side (hint)
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Diuretics - MOA in treating hypertension (acute effect)
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decreases blood volume
decreases CO |
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Diuretics - MOA in treating hypertension (chronic effect)
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decreases PVR
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First line for treatment of hypertension
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thiazide diuretic
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Why use Na channel blockers to treat hypertension (main)
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prevent hypokalemia from other diuretics
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remember these are K sparing diuretics |
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What CCBs decrease heart rate and force of contraction
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diltiazem and verapamil
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What effect does CCBs have on PVR?
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decreases
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A patient has hypertension and migraines. what would you use?
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beta blocker
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Which of the following drugs can cause edema?
metoprolol, nifedipine, ramipril or furosemide |
nifedipine
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A patient begins taking a drug for their hypertension. They complain of palpitations. What drug was it?
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alpha blocker, DHP CCB, vasodilator
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Side effect - constipation
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CCBs (mostly verapamil)
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Think of blocking contraction in the gut |
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MOA - ACE inhibitors treating hypertension
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decrease Ang II - decrease PVR
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Patient has hypertension and diabetes. What is the best drug to use?
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ACE inhibtor or ARB
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Patient has hypertension and kidney disease. What is the best drug to use?
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ACE inhibitor or ARB
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A patient has hypertension. They were put on a drug to treat it and subsequently went into kidney failure. It was discovered they had renal artery stenosis. What drug was most likely used?
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ACE inhibtor or ARB
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Patient is put on antihypertensive drug and they develop hyperkalemia. What was it?
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ACE inhibitor, ARB, renin inhibitor or aldosterone antagonist
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Patient is put on an antihypertensive drug and develops angioedema. What drug most likely caused this and what would you do about it?
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ACE inhibitor.
Switch them to ARB or renin inhibitor |
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What would you used in a patient with hypertension that is pregnant?
captopril, losartan, methyldopa? |
methyldopa
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MOA - alpha1 blockers in treating hypertension
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dilates arteries to decrease PVR
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Side effect - bradycardia, bronchospasm
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beta blockers
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Patient is on an antihypertensive drug. They stop taking it and their blood pressure shoots way up. What were they taking?
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beta blocker or clonidine
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MOA - clonidine
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alpha 2 agonist - works in CNS to decrease sympathetic outflow
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Side effect - dry mouth, sedation
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clonidine, methyldopa
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MOA - fenoldopam in treating hypertension
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Activates dopamine receptors - dialates arteries to decrease PVR
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MOA - nitroprusside in treating hypertension
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Produces NO - Diliates arteries and veins - mainly decreases PVR
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