• Shuffle
    Toggle On
    Toggle Off
  • Alphabetize
    Toggle On
    Toggle Off
  • Front First
    Toggle On
    Toggle Off
  • Both Sides
    Toggle On
    Toggle Off
Front

How to study your flashcards.

Right/Left arrow keys: Navigate between flashcards.right arrow keyleft arrow key

Up/Down arrow keys: Flip the card between the front and back.down keyup key

H key: Show hint (3rd side).h key

image

PLAY BUTTON

image

PLAY BUTTON

image

Progress

1/21

Click to flip

Card Range To Study

through

21 Cards in this Set

  • Front
  • Back
AP II: EXAM 2 CANCER THERAPY AND ANESTHESIA
AP II: EXAM 2 CANCER THERAPY AND ANESTHESIA
Radiation therapy
Causes breaks in DNA

Generates free radical

Formation of hydroxyl radicals--> leads to cell damage
Local side effects of radiation therapy
1. thyroid failure
2. inc. risk of MI
3. heart disease
Systemic effects of radiation therapy
1. fatigue
2. anorexia
3. GI
Chemotherapy
Drugs that treat cancers
What is adjuvant chemotherapy?
Given after surgery to destroy left over cells.
Neoadjuvant chemotherapy
Chemo given prior to surgery to "shrink" tumor so surgery is not so extensive.
Induction chemotherapy
Type that induces remission
Consolidation chemo
To maintain remission
Palliative chemo
Reduce symptoms w/o cure
Doxorubicin
Side effect causing heart damage.

Arrhythmias: WITHIN FIRST 24 HOURS following dose

Cardiomyopathy (deterioration of myocardium)
Multiple Uptake Gated Acquisition (MUGA) Scan
1. non-invasive
2. measures ventricular function
3. requires 1-2 hours
4. no signif adverse effects
How does MUGA scan work?
Radioactive tracer injected into veins.

Gamma camera takes pictures of ventricular function
Myelosuppression
Leads to deficiency of blood cells as a result of bone marrow suppression.

1. anemia
2. neutropenia (leads to inc. infection risk)
Cisplatin
Chemo drug used for cancer

Effect is limited in renal insufficiency pts. Most striking in the elderly.
Side effect of cisplatin
Nephrotoxicity

Ototoxicity (hearing loss)

Peripheral neuropathy
Bleomycin side effects
Interstitial pneumoitis

Pulmonary fibrosis (excess fibrous CT in lungs. Scarring of lungs). Collagen deposited in alveoli.
Hyperthermic Intraperitoneal Chemotherapy is useful for what type of cancers?
GI and ovarian cancers
When is Hyperthermic Intraperitoneal Chemotherapy administered?
In the OR after resection of masses but BEFORE reconstruction.
What are some anesthetic considerations for Hyperthermic Intraperitoneal Chemotherapy?
Fluid management

Temperature management
What is Hyperthermic Intraperitoneal Chemotherapy?
A type of hyperthermic therapy for cancer.

WARMED anti-cancer drugs are infused and circulated in the peritoneal cavity (abdomen) for a short period of time.