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46 Cards in this Set
- Front
- Back
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What is the pathology behind chronic mucocutatneous candidiasis?
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T cells dont mature and cant clear candida
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Which phagocyte disorder demonstrates a yellow NBT test?
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chronic granulomatous disease
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Which SLE nephropathy is considered the most severe?
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diffuse proliferative nephritis
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What the is the deficiency in Bernard-Soulier?
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Gp1b which binds von Willebrand factor to platelets
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What is the only inherited disorder that results in abnormal platelet and clotting factors function?
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vonWillebrand disease
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Lisch nodules are indicitave of what disease?
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NF1 (von Recklinghausen)
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What cancer are people with von Hippel Lindau at particular risk for?
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renal cell carcinoma
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What is the pathology behind ataxia-telangiectasia?
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DNA repair enzymes don't work
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What is the trinucleotide repeat in Fragile X disease?
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CGG
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What is the classic triad of Wiscott-Aldrich syndrome?
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otitis media, eczema, thrombocytopenia
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Which chromosome 15 deletion syndrome is associated with severe hypotonicity as an infant, obesity, and mental retardation?
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Prader-Willi
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What disease is associated with HLA-DR2 and intention tremor?
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Multiple sclerosis
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What is the most common cause of osteomyelitis in IV drug abusers?
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pseudomonas or serratia
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What is the most common cause of septic shock?
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Gram negatives
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What is the mechanism of action for amantidine and rimantidine?
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they bind the M2 receptor on influenza A and prevent the uncoating of the virus
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What group of viruses does vidarabine kill?
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all the herpes viruses (HSV1-2, EBV, CMV, varicella-zoster)
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Which drugs are the neuraminidase inhibitors?
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zanamivir, oseltamivir
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Which antiviral drug is nephrotoxic (Fanconi) and teratogenic?
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cidofovir
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Which bone disease is associated with a lack of Vit D and an elevated alk. phosphatase?
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osteomalacia
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Which bone disease is associated with a mosaic pattern and extremely high alk. phosphatase?
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Paget's disease
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What type of cartilage is developing bone?
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type II (hyaline)
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Which benign bone tumor is extremely painful?
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osteoid osteoma
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What does Codman's triangle on an X-ray mean?
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osteosarcoma
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Which muscular dystrophy is associated with pseudohypertrophy of calves?
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Duchenne (the most common one)
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What is the most common supratentorial tumor in children?
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craniopharyngioma
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Lewy bodies represent what CNS disease?
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Parkinson's
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Oligoclonal bands is most likely tto represent what disease?
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Multiple sclerosis
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What two hormones do eosinophile cells in the anterior pituitary produce?
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GH and prolactin
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What is the tumor of the adrenal medulla called?
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pheochromocytoma
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What thyroid disease results in fibrous replacement of thyroid tissue?
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Riedel's
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Between papillary carcinoma and follicular carcinoma of the thyroid, which is more common and also less aggressive?
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papillary
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How can chronic renal failure cause bone osteodystrophy?
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dont excrete phosphate and it binds to calcium causing hypocalcemia which triggers PTH to activate osteoclasts and demineralize bone
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What effect does gestational diabetes have on the fetus?
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fetus releases more insulin to make up for the lack that the mother prdouces and results in fetus gaining weight and more likely for birth trauma
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Which multiple endocrine neoplasia is associated with gastrinoma?
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MEN1
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What skin disease is associated with squamous cell carcinoma in situ?
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Bowen's disease
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What disease is cavernous hemangioma associated with?
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Sturge-Weber
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Vinyl chloride poisoning is most associated with which cancer?
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liver angiosarcoma
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What disease is associated with the depigmentation of the substantia nigra?
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Parkinson's
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What organ can you sometimes find a Ghon complex?
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lung
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India ink staining is used for what?
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cryptococcus
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What are the Hardy-Weinberg equations?
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p^2 + 2pg q^2= 1
p + q= 1 |
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The head of rib 11 would articluate with the inferior facet of which vertebral vertebra?
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T10
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What makes rib T2 atypical?
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it has an extra rib tuberosity
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Which ribs are the true ribs?
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1-7
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What are the primary muscles of respiration?
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intercostals, diapraghm
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What is the anatomical landmark to find T4?
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Sternal angle (angle of Louis)
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