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14 Cards in this Set
- Front
- Back
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Leukotrienes
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chemical mediators of inflammation stored and released by mast cells; effects are similar to those of histamine
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Methylxanthine
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chemical derivative of caffeine; alternative bronchodilators, prescribed for persistent chronic asthma.
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Dry powder inhaler (DPI)
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device used to convert a solid drug to a fine powder for the purpose of inhalation
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Chronic bronchitis
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recurrent disease of the lungs characterized by excess mucus production, inflammation, and coughing
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Chronic obstructive pulmonary disease (COPD)
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generic term used to describe several pulmonary conditions characterized by cough, mucus production, and impaired gas exchange
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Salmeterol (serevent) bronchodilator/ beta 2 adrenergic agonist
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acts by selectively binding to the beta 2 adrenergic receptors in bronchial smooth muscles to cause bronchodialation. can prevent exercise induced bronchospasms. Better suited for tx of chronic asthma due to it's duration. onset 10-20mins, duration up to 12hrs.
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Ipratropium Bromide (atrovent, combivent)
Bronchodilator/ anticholinergic |
anticholinergic that causes bronchodilation by blocking cholinergic receptors in bronchial smooth muscle. also prescribed for chronic bronchitis and nasal congestion. onset 5-15 mins, duration 3-6 hrs. bitter taste, rinse mouth,
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Beclomethasone (Beclovent)
Inhaled glucocorticoid |
glucocorticoid, available thru aerosol inhalation (MDI) for asthma or as a nasal spray for allergic rhinitis. Acts by reducing inflammation, decreasing frequency of asthma attacks.
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Zafirlukast (Accolate)
Leukotriene modifier |
used for the prophylaxis of persistent, chronic asthma. Blocks leukotrine receptors in the airways. onset 1 wk. adverse effects most common HA.
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aerosol
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suspension of minute liquid droplets or fine solid particles suspended in a gas- delivers the drugs to their immediate site of action (immediate relief for bronchospasms)
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bronchodilators
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most commonly used for treating pulmonary disorders, stimulate beta 2 adrenergic receptors to dilate bronchioles
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MDIs
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use a propellant to deliver a mesuared dose of drug to the lungs during each breath. disadvantages- precise does received difficult to measure
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for treatment of acute bronchoconstriction
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beta-adrenergic agonists- activate both beta 1 and 2 receptors (severent)
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leukotriene modifiers
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oral medications approved for the prophylaxis of chronic asthma- reduce inflammation and ease bronchoconstriction
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