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8 Cards in this Set
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- Back
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Treatment ra
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Anti- TNFalfa-monoclonal anibody:
Infliximab Or Anti-B cell monoclonal antibody Rituximab And corticosteroids |
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What is ms (multiple sclerosis)
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AID to myelin sheath of nerve cells causing sclerosing plaques of demyelinated tissue in the white matter in the cns.
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Diagnostic ms
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Plaques: MRI
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Symptoms ms
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Motor weakness
Impaired vision Lack of coordination Spasticity |
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Pathof ms
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Th1, MF, ifngamma
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Patho mg
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Ab block and induce endocytosis and degradation of receptors of the neuromuscular junction as ACh and calciumchannels.
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Treatment mg
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Pyridostigmine: Cholinesterase i: raises concentration ACh in junction, competes with ab for receptor.
Azathioprine: reduces ab production |
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Symptoms mg
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Muscle weakness
Droopy eyelids Double vision Facial weakness Chest impairng breathing |
