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3 Cards in this Set
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Barbituates:
have lots of tolerance...have been replaced by benzos due their physical dependence and severe withdrawal symptoms interfere with the Na/K transport system of cell membranes. increase GABA action and increase chloride entry into the neurons Do not use in pts with acute intermittent porphyria bc increase porphyrin synthesis ADRs: drowsiness, decreased concentration, physical sluggishness, drug hangover, and has severe withdrawal symptoms |
Phenobarbitol:
long acting (1-2days) used in long term seizure disorder control of status epilepticus and eclampsia DOC for children with recurrent febrile seizures it is rarely used as a hypnotic |
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Thiopental
only given via IV it is short acting used for anesthesia |
Chloral hydrate:
Non-barbiturate hypnotics: derivative of acetylaldehyde indices sleep in 30 min and acts for 6 hrs has a very unpleasant taste |
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Meprobamate:
carbamate derivative with tranquilzing muscle relaxant and anticonvulsant activity |
complete
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