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24 Cards in this Set

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Q. Fructose is controlled or uncontrolled in the body?
uncontrolled
Q. fructose insertion point is?
AFTER PFK1
Q. Fructose energy yield is?
38 ATP
Q. Fructose blocks break down of?
glycogen in the liver
Q. High fructose leads to?
hypoglycemia
Q. Enzyme used in the in the Fructose to fructose-1-phosphate?
fructokinase
Q. Enzyme used when fructose 1-phosphate splits (cleaves) to DHAP and glyceraldehyde?
Aldolase B
Q. Enzyme used when Glyceraldehyde goes to PGAL?
Glyceraldehyde Kinase
Q. Fructose inserts in three places in glycolosis?
Fruc >Fruc 6 P
DHAP (step 2) > PGAL
Glyceraldehyde > PGAL
Q. What enzyme is affected in Essential fructosuria?
Fructokinase
Q. What is the diagnosis of Essential fructosuria?
High fructose concentration in urine
Q. Treatment of Essential fructosuria?
Lower fructose intake
Q. What enzyme is affected in hereditary fructose intolerance?
Aldolase B
Q. Diagnosis of hereditary fructose intolerance?
urinate F-1-P, very hypoglycemic
Q. What disease is caused by the Phosphates removal from the body through hereditary fructose intolerance?
gout
Q. Gout is characterized as?
uriate crystals forming in the joints
Q. Treatment of hereditary fructose intolerance
removal of fructose and sucrose from diet
Q. What are the pathophysiological changes in the body due to hereditary fructose intolerance?
hypophosphatemia, hypermagnesia, hyperuricemia, hypoglycemia
Q. hypermagnesia?
Increased levels of “unbound”/“free” magnesium due to removal of phosphate
Q. Hypophosphatemia?
Abnormally low levels of phosphate in the blood
Q. What vitamin is the substitute for the role of the parathyroid hormone?
Vitamin D
Q. Hyperuricemia?
High levels of uric acid in the blood
Q. Hypoglycemia?
Low blood glucose
Q. Vitamin D is triggered by?
Low phosphate levels in the blood