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160 Cards in this Set

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What is the method of reasoning that uses construction of general principles by careful examination of hypotheses
Inductive Reasoning
What does life require?
Order
Sensitivity
Regulation
Growth
Development
Reproduction
A Hypothesis..
Does not always withstand the test of experiments, therefore it may be rejected in the light of new information.
The Scientific Process involves
rejection of the hypothesis that is inconsistent with experimental results.
Evolution
One type of organism can change gradually into another type over a long period of time.
Evolution Requires
Natural Selection
Adaptation
Genetic Variation
Change over time
Experimental Design
A blueprint of the procedure that enable the researcher to test his hypothesis. Conceptual framework within which the experiment is conducted setting up plots to observe an experimental organism
Long Term Population Study
Include a comparison population to act as a control that would ensure the results obtained were due to differences in only one variable.
Body Shivering
Attempt to regulate the body's temperature - HOMEOSTASIS
Organisms are composed of
Molecules, which are made of smaller components called atoms.
Negatively charged particles of atoms with almost no mass are called what?
Electrons
Elements that have atoms with the same atomic number but different number of neutrons are called
Isotopes
A gain of electrons is known as
Reduction
When atoms gain or lose electrons, they become negatively or positively charged. These are known as
Ions
In the crystal matrix of ordinary salt, the sodium and the chloride are connected by what kind of bonds?
Ionic
Non-polar molecules tend to aggregate in water because they are forced to come into close proximity to each other due to.
Hydrophobic interactions
The half life of Carbon 14 is 5,600 years.
This means that the mass of 88 grams would be reduced to:
44 in 5,600 years
22 in 11,200 years
The most accurate endo-membrane route through which a protein is secreted from a cell is through:
Endoplasmic Reticulum
Golgi Apparatus
Vesicles
Plasma Membrane
Ribosome is involved in
Protein Synthesis
Enzymes in lysosomes in a cell help to
prevent excess accumulation of lipids and other organic molecules within those cells
Mitochondria are involved in
Production of ATP
Proteins of the plasma membrane are in large part responsible for the cell's ability to interact with it's environment.
They act as or are involved in channels, recognition, transport and reception.
A cell wall is not present in
all eukaryotic cells.
Nucleolus of the nucleus is the site of
ribosome assembly
The phospholipids are arranged to form the plasma membrane as a
double layer with hydrophobic tails facing inwards toward each other.
Micro tubules and micro filaments are the primary components of
the cytoskeleton
Macromolecules are disassembled in
hydrolysis reactions
Relatively small organic molecules with a central carbon atom bonded to a carboxyl group, an amino group, a carbon containing group, and a hydrogen atom are
amino acids
DNA are macromolecules that
store hereditary information for organisms
Humans are unable to get metabolic energy from cellulose because we
lack the cellulose digesting enzymes.
A common lipid for energy storage are
triglycerides
Components of nucleic acids include
a five carbon sugar,
a phosphate group,
an organic nitrogen containing a base, and phosphodiester bonds
Within DNA
A - T
G - C
A protein has
a carboxyl end and is made of amino acids
Hydrogen bonds between different parts of the polypeptide chain result in
secondary level of protein structure
When a protein is composed of more than one polypeptide chain, the arrangement of the chains is called
the quaternary structure
The plasma membrane is a thin sheet of
lipids embedded with proteins
If two solutions have unequal concentrations of solute, which is hypotonic?
The solution with the lower concentration
If a blood research laboratory is attempting to collect the content of human red blood cells, what kind of solution should they use to prevent the cells from lysing (bursting)
isotonic
During neuronal signaling, a change in membrane potential will cause sodium channels to open and let Na+ ions diffuse down their concnetration gradeient into the cell.
This gradient is the Na+/K+ pump
Glucose transport across a membrane requires the help of a
protein
The plasma membrane is composed of an extracellular and intracellular layer of phospholipids and contains
glycolipids
glycoproteins
peripheral proteins and integral proteins
Carbon Dioxide and oxygen gas passes through a lipid bilayer
most readily
Following a meal, glucose must move from the gut lumen where there is a high glucose concentration into the intestinal cell where there is a low concentration of glucose. This is called
Facilitated Diffusion
At least 90% of organisms on earth are
heterotrophs:
fungi, eubacteria, animals and most plants
The first stage of cellular respiration and the oldest in terms of evolution is
Glycolysis
An electron carrier that is used in harvesting energy from glucose molecules in a series of gradual steps in the cytoplasm is
NAD+
Altering the 3d structure of an enzyme might prevent the substrate from binding to
its active site
For a reaction to occur, the free energy released from the hydrolysis of ATP would have to be _______ than the free energy of the reaction.
Greater
Useable free energy is negative and
an endergonic reaction has a positive free energy. (delta G)
The amount of energy available to do work is
Free Energy
Water behind a dam would be the best
reflect of potential energy
A competitive inhibitor enzyme competes for
substrate binding sites on the enzyme
The 2nd Law of Thermodynamics states that
disorder in the universe is continually increasing.
When a chemical has been oxidized, it means that
it has lost electrons to another chemical in the reaction.
The sites where molecules other than substrates bind in an enzyme to alter its activity are called
allosteric sites.
Enzymes have specific substrates with which they
interact
The movement of sucrose and H+ into the cell by a common membrane protein reflects
transport through a symporter
Water diffuses through certain organs such as the kidneys an bladder much faster than they would elsewhere through
passive diffusion through a lipid bilayer alone because of aquaporin channels.
The reaction C6H12O6 +6O2 = 6CO2+ H2O when it occurs in living cells is
aerobic respiration
1 glucose molecule can power the krebs cycle
for two turns
The enzymes of the krebs cycle are located in the matrix of the
mitochondria
Certain liver cells have a cell cycle of about
1 year
The attachment of microtubules is critical for the proper separation of
sister chromatids
Interphase is represented by
G1 + G2 + S
The first stage of mitosis - PROPHASE
the chromosomes become visibly shorter and thicker
Some of the portions of the chromatin, heterochromatin, are permanently condensed so that their DNA
is never expressed
The division of a bacterial cell occurs as the plasma membrane pinches inward
constricting the cell
the bacterial genome exists as a single, circular, uncoated, double stranded
DNA molecule
If a eukaryotic cell has a single set of chromosomes it is
haploid
Two species of frogs have similar ranges, but Rana aurora breeds from January to March, while Rana boylii breeds from March to May. This is an example of
Temporal Isolation
Species evolve continuously over long spans of time according to the concept of
gradualism
Chromosomes exchange genetic information by crossing over.
This takes place in prophase I
Between the two divisions of meiosis, there is no
S phase.
The synaptonemal complex is a lattice of proteins that holds
homolouges together
Meiosis and mitosis are both processes that involve nuclear division.
Mitosis: Diploid somatic cells
Meosis: Haploid gametes
Genetic recombination leading to an increase in variability is possible because of
independent assortment, crossing over, and fertilization with a non-related gamete
Unique features of meiosis are
synapsis, haploid daughter cells, and reduction division
In anaphase 1 homologous chromosomes separate
in anaphase II chromatids separate
The purpose of meosis I is to
separate homologous chromosomes
In humans, gametes are haploid
Somatic cells are diploid
A diploid organism that has two identical alleles for the same trait is said to be
homozygous for that trait
The allelic makeup of an individual is
their genotype
The observable outward appearance of the genes of an individual is their
phenotype
The concept that offspring can inherit the acquired skills of their parents is called
blending inheritance or Lamarck's Hypothesis
In humans, having dimples is dominant. If a child has dimples and only one of her parents does,
one parent must be dd and her parent could be Dd or DD
In simple mendelian inheritance, the protein produced by a single allele can produce:
The dominant phenotype
When a single gene mutation can have phenotype effects at multiple stages of development, it is
pleiotropic
The probability of a couple having a daughter is
50%
Organisms generally have many more genes that assort independently than the number of chromosomes.
This is due to crossing over
In Drosophila, the sex of an individual is influenced by the number of copies of its
X-Chromosomes
Genetic exchange between two arms of a chromosome pair is more likely to occur if the distance between them is great.
Crossing Over
If some alternative alleles with detrimental effects exist in significant proportions in populations, the condition is called a
genetic disorder
Amniocentesis
A procedure that is normally used for diagnosis of genetic disorders
A test cross can be used to determine whether an individual that displays a dominant phenotype is homo or hetero
gathers phenotypic and genotypic information
In humans, if non-disjunction event led to an individual with XXY they would be a
Male because of the Y chromosome
Non disjunction led to XO, they would be
Female due to the lack of the Y chromosome
As genetic distance increases, the recombination frequency first increases in a linear fashion, but then levels off to about
0.5
The enzyme that catalyzes the synthesis of new DNA molecules is
DNA Polymerase III
The chemical bond connecting one nucleotide with the next along the nucleic acid chain is called
a phosphodiester bond
Chargaff's Rules for the pairing of nitrogen bases is
A to T and G to C
The lagging strand is discontinuous
Okazaki fragments replicate the strand.
the site of the opening of DNA strands where active replication occurs
The Replication Fork
The DNA double helix is similar ladder that is twisted with
alternating units of phosphate groups and sugars
Uracil
NOT found in DNA
DNA
Adenine and Thymine - 2 H+ bonds
Guanine and Cytosine - 3 H+bonds
Criteria for genetic material
must contain information necessary to construct a whole organism, transmitted from parent to offspring, must account for known variation and it must be replicated
the nucleotide sequence of mRNA codon
composed of 3 bases
In eukaryotic cells, mRNA is made as
a complementary copy of the information found in the DNA strand
64 unique mRNA codons can be constructed from
the four mRNA nucleotides
the bond that forms between the newly added amino acid and the previous amino acid is called a
peptide bond
In eukaryotes, the empty RNA molecule exit the ribosome from the
E site
The Central Dogma of biology is stated as
DNA and RNA proteins
Pre-mRNA is first produced from the
transcription of a eukaryotic gene
RNA polymerase is to transcription as ribosomes are to
translation
A gene is an organized unit of DNA sequences that enables a segment of DNA to be transcribed into
RNA and ultimately results in the formation of a functional product.
The components of the translation machinery are
mRNA, tRNA, translation factors and ribosomes
Disassembled sponges
will re aggregate by species
Organisms develop a normal morphology because cells can receive and interpret both
extracellular and intracellular positional information
The cellular processes for limb formation in correct order from first to last is
cell division
cell migration
cell differentiation
cell death
To determine the function of a vertebrate gene by creating a mutant strain,
Drosophila would be most suitable
Desirable characteristics in a model organism to study development are
short generation time
small size
large oocytes
produce many offspring
The operator is a site of negative genetic regulation
binding by repressor blocks transcription
An operon is a cluster of functionally related genes encoded into a mRNA molecule.
a mode of prokaryotic gene regulating unit.
A protein that initiates the transcription of genes which allow the use of non-glucose molecules is the
CAP
A protein that regulates transcription by binding to the operator is the
repressor
A well-understood transcriptional activator of E.Coli, which initiates the transcription of genes in non-glucose environments is called
catabolite activator protein (CAP)
in gene regulation, a gene is turned on by
an activator
The zinc finger, helix-turn-helix, homeodomain and leucine zipper are all examples of shapes in regulatory proteins which are used to
bind DNA
The DNA binding proteins of almost all regulatory proteins employ structural motifs that enable them to fit into the major groove of the
DNA
Control of gene expression enable bacteria to adapt to changing environments and multicellular organisms to
develop, function as a whole, and maintain homeostasis.
All regulatory proteins have common DNA binding motifs
These are particular bends in their protein chains that permit them to interlock with the major groove of the DNA helix.
The founder effect is the loss of:
genetic variation that occurs when a new population is established by a very small number of individuals from a larger population
Evidence for evoluton
early development
vestigial structures
patterns of distribution
convergence
the evolution of different forms in the same lineage when exposed to different selective pressures is called
divergence
The features of feathers on Archaeopteryx clearly demonstrates that it was on the evolutionary line of
dinosaurs to birds
The side toes of horses, pelvic bones of whales, and the human appendix are all
vestigial structures
Biological Evolution is defined as
heritable changes in characteristics across generations
A group of related organisms that share a distinctive form is called a
species
Molecular evolution refers to molecular changes in genetic material that lead to
phenotypic changes
when looking at dogs, the major difference between natural selection and artificial selection is
how the parents are chosen
Transfer of a functional domain from one gene to another, creating a novel protein, can occur by
exon shuffling
the model that assumes that evolution proceeds with slow successive change in a given line is called
gradualism
the type of speciation that occurs geographically is called
allopatric speciation
Isolating mechanism that leads to reproductive isolation by preventing hybrid zygotes is called
prezygotic isolating mechanism
Two groups of organisms that differ from one another in one or more characteristics and do not hybridize extensively if they occur together in nature are
considered to be different species
The organization phases of development are regulated by
morphogens, transcription factors, and segmentation genes
The majority of Drosophila embryo segments will become part of the
abdomen
Homeotic genes encode transcription factors
found in clusters called complexes activate developmental genes and a portion of these proteins can bind DNA
A blastomere is the result of a tremendous increase in the number of cells, clustered by a
decrease in the size of the cells
Totipotency occurs very early in development.
Each cell is capable of expressing all of its genes
The founder principle explains how rare alleles may become more common in
new populations
a restriction in genetic variability caused by a drastic reduction in population size is called
bottleneck effect
The genetic contribution of an individual to succeeding generations compared with that of other individuals is known as
fitness
In the Hardy-Wienburg equations,
frequency of 2 alleles - p and q
When selection acts to eliminate one extreme from an array of phenotypes, it is called
directional selection
Migration would be expected to produce the ________ evolutionary change in a population over time
largest
Extreme sexual selection would change the _______________ of a population
allele frequencies
All the members of a single species that occupy a particular area at the same time are known as a
population
A certain species of butterfly range from white to dark blue. The birds feed on the lighter or white butterflies. Leaving butterflies that are darker colored. This may result in
directional selection