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16 Cards in this Set
- Front
- Back
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Mitosis
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process of cell division (occurs in actively dividing tissues; growth and development)
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the “objective” of mitosis
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produce two cells (daughter cells) from one
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if the daughter cells are to be functional they each must have...
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a full complement of DNA and all the required organelles
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• mitosis as a process is principally concerned with ...
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how each daughter cell gets a full complement of DNA
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Names of Stages of Mitosis
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Interphase
Prophase Metaphase Anaphase Telophase |
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Interphase
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- sometimes called the “resting” phase
- nucleus is well defined with nucleoli - chromosomes are not visible - DNA is replicated during this phase, but the cell exhibits no outward manifestation of this process - centrosomes duplicates and both are located to the same side of the nucleus |
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Prophase
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- nuclear membrane disappears
- nucleoli disappear - chromosomes condense, each is now comprised of two (sister) chromatids that are held together by a centromere - centrosomes begin to migrate to the poles of the cell and the mitotic spindle begins to form |
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Metaphase
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- fully formed spindle at the cellular poles
- duplicated chromosomes align along the equatorial plate - spindle fibers attach to the a special region of centromere called the kinetochore (each chromatid now has a centromere and kinetochore) |
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Anaphase
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- spindle fibers contract and pull sister chromatids apart
- each chromatids is now called a chromosome - chromosomes move toward the poles of the cell |
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Telophase
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- nuclear membranes begins to form around the chromosomes
- chromosomes decondense somewhat - cytokinesis occurs animal - cleavage furrow plants - formation of a cell plate |
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Three Aspects of Interphase
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1. G1 - growth phase (cell enlargement)
2. S (DNA replication; chromosomes copied) 3. G2 (cell enlargement continues) |
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Two Aspects of Mitotic Phase
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• mitosis (karyokinesis) - division of the nucleus
• cytokinesis - division of the cytoplasm |
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Regulation of the Cell Cycle
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• Events that occur during the cell cycle are regulated by a group of proteins called protein kinases
• The activity of protein kinases moves the cell through checkpoints in the cycle |
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Control of the Cell Cycle
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Mitosis and Meiosis
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• Mitosis
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produces daughter cells which maintain a standard number of chromosomes; two daughter cells result
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• Meiosis
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produces daughter cells which have half the number of chromosomes; four daughter cells result
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