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213 Cards in this Set

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The viral reproductive cycle characterized by integration of the bacteriophage nucleic acid into the host bacterium's genome
Lysogenic cycle
When a virus has integrated its DNA into the host's genome, it's called a:
prophage
Have a thin peptidoglycan layer and stain pink
Gram-negative bacteria
Have a lipopolysaccharide layer
Gram-negative bacteria
Have a thick peptidoglycan layer and stain purple
Gram-positive bacteria
Protein coats that contain DNA or RNA
Viruses
Enzyme that converts the viral RNA to DNA, which is then integrated into the cell’s chromosome
reverse transcriptase
A primary connection between the nervous system and endocrine system
Hypothalamus
A cross between two individuals results in a ratio of 9:3:3:1 for four possible phenotypes. This is an example of a:
Dihybrid cross
Analogous structures in organisms are the result of…
Convergent evolution
A potential problem with the chromosomal theory of inheritance is that there are many more ____ that assort independently than there are ________
traits; chromosomes
an abnormal chromosome number
aneuploidy
Accidental changes in genes
Mutations
an incurable disorder in which some Ashkenazi Jews' brains deteriorate
Tay-Sachs disease
According to ________, giraffes evolved long necks because ancestral giraffes tended to stretch their necks and this neck extension was passed on to subsequent generations
Jean-Baptiste Lamarck
According to _______, the variation is not created by experience, but already exists when selection acts on it
Darwin
__________ states that species experience long periods of little or no evolutionary change (termed ____), interrupted by bursts of evolutionary change
Punctuated equilibrium; stasis
because the proportions of genotypes do not change from generation to generation, the genotypes are said to be in:
Hardy-Weinberg equilibrium
a change in a nucleotide sequence in DNA
Mutation
______ are generally too low to significantly alter Hardy-Weinberg proportions
Mutation rates
a breeder selects for the desired characteristics
artificial selection
a form of selection that occurs when selection acts to eliminate one extreme from an array of phenotypes
Directional selection
______ cell mutations don't affect gametes
somatic
Capsules are thick and __________ in shape
definite, uniform
A ____________ bacterial cell well is 80 to 90% peptidodoglycan
Gram-positive
A ____________ bacterial cell well is 80 to 90% peptidodoglycan
Gram-negative
Occurs when homologous chromosomes or sister chromatids fail to separate during meiosis
Nondisjunction
Features that have a similar function but different structural origin are called…
Analogous structures
Features that have a different form or function but similar structural origin are called…
Homologous structures
Homologous structures in organisms are the result of…
Divergence
The virus reproductive cycle where the virus enters the cell, uses the cell structures to make more viruses, then bursts open the cell to release the new viruses
Lytic cycle
when crossing individuals who are true-breeding for two different characters, the F1 individual that results is a:
dihybrid
Name the law:
the two alleles of a trait separate from each other during the formation of gametes, so that half of the gametes will carry one copy and half will carry the other copy
Mendel’s First Law: Segregation
Name the law:
genes located on different chromosomes are inherited independently of one another
Mendel’s Second Law: Independent Assortment
The chromosomal theory of inheritance was first proposed in 1902 by:
Walter Sutton
Experimental study of this creature by Thomas Hunt Morgan provided confirmation of the chromosomal theory of inheritance
the fruit fly (Drosophila melanogaster)
The vehicles of Mendelian inheritance
chromosomes
The mutant male fruit fly with white eyes demonstrated a __________ trait
sex-linked
traits assort independently because _________ assort independently
chromosomes
the tendency of close- together genes to segregate together
Linkage
the further two genes are from each other on the same chromosome, the ___ likely crossing over is to occur between them
more
Down syndrome is caused by having:
an extra copy of chromosome 21
Name chromosomal disorder: Usually taller than average but other symptoms vary
XXX female
nondisjunction of the X chromosome creates three possible viable conditions (name the chromosome arrangements)
XXX, XXY and XO
Name chromosomal disorder:
sterile male with many female characteristics and
diminished mental capacity
Klinefelter syndrome
Name chromosomal disorder:
sterile female with webbed neck and diminished stature
Turner syndrome
Nondisjunction of the Y chromosome leads to ___ males
XYY
mutations occur only rarely and almost always result in _____ alleles
recessive
one can identify which relatives exhibit a trait by looking at family trees or:
pedigree
Pedigree key:
Circles represent _______
females
Pedigree key:
Squares represent _______
males
Pedigree key:
White means ______
unaffected
Pedigree key:
Black means _____
Affected
Pedigree key:
Half black half white means _____
Carrier
People with sickle-cell anemia carry a mutated gene that produces a defective version of _______
Hemoglobin
Why is sickle-cell anemia more common than Tay-Sachs?
Tay-Sachs sufferers die by age five, sickle-cell carriers have adaptive advantage
genetic disorder caused by a dominant allele, causes progressive deterioration of brain cells
Huntington's disease
fetal cells from the chorion in the placenta are
removed for analysis
Chorionic villus sampling
when amniotic fluid
is sampled and isolated fetal cells are then grown in culture and analyzed
Amniocentesis
Genetic counselors look at 3 things from the cell cultures obtained from either amniocentesis or chorionic villus sampling:
1. chromosomal karyotype
2. enzyme activity
3. genetic markers
most recent form of genetic counseling
DNA screening
procedure where parents conceiving by in vitro fertilization (aka. “test-tube babies”) can screen zygotes for potential genetic anomalies
preimplantation screening
large scale patterns, trends, rates of change among groups of species
Macroevolution
cumulative genetic changes that give rise to new species
Microevolution
changes that occur within a species that make that species different from its immediate ancestor
Microevolution
results from microevolutionary changes that increase the likelihood of survival and reproduction of particular genetic traits in a population
adaptation
predecessor to Darwin who proposed that evolution occurred by the inheritance of acquired characteristics
Jean-Baptiste Lamarck
states that evolutionary change occurs extremely slowly
Gradualism
the most direct evidence of macroevolution
fossil records
the preserved remains, tracks, or traces of once-living organisms
fossils
structures that have no function
Vestigial structures
changes in an individual gene, compared over a broad array of organisms, dated from the time of divergence
molecular clock
study of the properties of genes in populations
Population genetics
the sum of all of the genes in a population, including all alleles in all individuals
Gene pool
in a large population in which there is random mating, and in the absence of forces that change allele frequencies, the original genotype proportions __________ from generation to generation
remain constant
Different traits exist in a population in varying _______
frequencies
If the proportions of a genotype remain constant from generation to generation, they are in:
Hardy-Weinberg equilibrium
the proportion of individuals with a certain characteristic compared to an entire population
frequency
knowing the frequency of the phenotype, one can calculate the frequency of _____ and ____ in the population
genotypes and alleles
The Hardy-Weinberg equilibrium only works if the following 5 assumptions are met:

1. The size of the population is _____
2. Individuals can mate with one another __________
3. There is no ________
4. There is no ________ or ______
5. All alleles are ________ ______ from generation to generation
1. very large or effectively infinite
2. at random
3. mutation
4. immigration or emigration
5. replaced equally
the frequency of heterozygote carriers for recessive genetic disorders can be estimated using:
the Hardy-Weinberg rule
mutations must affect the DNA of _________ or the mutation will not be passed on to offspring
the germ cells
no matter how rare, ______ is the ultimate source of variation in a population
mutation
the movement of individuals between populations
Migration
the magnitude of the effects of migration is based on 2 factors:
1. proportion of migrants
2. difference in allele frequencies b/w migrants, original population
random changes in allele frequencies
Genetic drift
in small populations, the frequencies of particular alleles may be changed drastically by ________
chance alone
occurs when one of a few individuals migrate and become the founders of a new, isolated population at some distance from their place of origin
founder effect
when a population is drastically reduced in size
bottleneck effect
when individuals with certain genotypes mate with one another either more or less commonly than would be expected by chance
Nonrandom mating
choosing a mate based on, often, physical characteristics
sexual selection
nonrandom mating alters _______ frequencies but not ______ frequencies
genotype; allele
occurs if some individuals leave behind more progeny than others
Selection
conditions in nature determine which kinds of individuals in a population are the most fit
natural selection
form of selection in which both extremes from an array of phenotypes are eliminated
Stabilizing selection
form of selection in which the two extremes in an array of phenotypes become more common in the population
Disruptive selection
when the payoff in survival of heterozygotes makes up for the price in death of homozygotes
heterozygote advantage
Selection on color in guppies is an example of:
disruptive selection
The protective external covering of a prokaryotic cell is called _________ and consists of what three layers?
Cell envelope;

– Glycocalyx
– Cell wall
– Cell/plasma membrane
Glycocalyx subdivides into:
capsule and slime layer
General term for structures found outside of the cell wall (extracellular)
Glycocalyx
Polysaccharide layer of prokaryotic cell – sticky, complex sugars
Glcocalyx
Functions include communication b/w cells, interaction w/ other ECMs, anchoring of cells, protection from pathogens, involved in the (human) immune response, and formation of biofilms
Glycocalyx
Steps in prokaryotic cell division
DNA replication + binary fission
Conduits of bacterial genetic transfer, and what they transmit
Pili; plasmids
Contributes to bacterial cell virulence by protecting it from phagocytosis and drying
Capsule
Protects bacterial cell from drying, promotes adherence
Slime layer
Protective outer layer of bacterium composed of peptidoglycan (a glycoprotein)
Cell wall
The bacterial cell wall is composed of (specifically):
peptidoglycan (a glycoprotein)
Provides a bacterium strength against osmotic pressure and determines the results of Gram's stain
Cell wall
Site of action of antimicrobial drugs such as penicillins
Cell wall
The plasma membranes of Gram-______ bacteria are encased within a porous cell wall of peptidoglycan
positive
In Gram-______ bacteria, the peptidoglycan layer is thin and covered by an outer layer of __________
negative; lipopolysacharride
Tay Sachs is caused by a defective allele on what chromosome?
chromosome 15
Huntington's is caused by a defective allele on what chromosome?
chromosome 4
Sickle cell anemia is caused by an allele on what chromosome?
chromosome 11
Changes in allele frequency lead to ____evolution
microevolution
When the same parts have different functions on different species, it's morphological _________
morphological divergence
When different parts have similar functions on different species, it's morphological _________
morphological convergence
The polysaccharide (sticky sugar) layer is what part of the cell envelope?
Glycocalyx
A bacterium with both a capsule and a slime layer is:
Impossible
Stains purple
Gram-positive
Stains pink
Gram-negative
Spherical bacterial shape
cocci
Rodlike bacterial shape
bacilli
Bacterial arrangement in pairs
diplo
Bacterial arrangement in chains
Strepto
Bacterial arrangement in bunches
Staphylo
Use the energy of sunlight to build organic molecules from CO2
Photoautotrophs
Obtain their energy by oxidizing inorganic substances
Chemoautotrophs
Use sunlight for energy but obtain carbon from organic
molecules produced by other organisms
Photoheterotrophs
Obtain both carbon atoms and energy from organic molecules
Chemoheterotrophs
HIV recognizes ___ surface marker on macrophages and,
later, T cells
CD4
What marks onset of AIDS?
Infection and destruction of T cells
Pili are composed of:
Pilin protein
Sex pili are also called:
conjugation bridge
Bacterium with one flagellum
Monotrichous
Bacterium with multiple flagella located at the same spot on the bacterium's surface
Lophotrichous
Bacterium with flagella located on opposite sides of the bacterium's surface
Amphitrichous (technically only one on each side, but that's not what diagram says)
Bacteria with flagella projecting in all directions
Peritrichous
Thick walled resistant body around genetic material
Endospores
Allows bacteria to resist environmental stress (extreme temps, drying, radiation, chemicals)
Endospores
Bacteria with endospores are in a _______ state
dormant
Can be free-floating or integrated into bacterial chromosome
Plasmid
Extra-chromosomal genetic element that may confer protective traits to bacteria
Plasmid
Changes in allele frequency leading to microevolution can be due to:
natural selection or genetic drift
when some individuals leave behind more progeny than others
Selection
If a macromolecule has an R group it is a ______
protein
sucrose is a combination of
glucose + fructose
Monosaccharide or disaccharide:
Galactose
Monosaccharide
Monosaccharide or disaccharide:
Lactose
disaccharide
Monosaccharide or disaccharide:
Glucose
Monosaccharide
Monosaccharide or disaccharide:
Maltose
disaccharide
Monosaccharide or disaccharide:
Fructose
Monosaccharide
Monosaccharide or disaccharide:
Sucrose
disaccharide
What is maltose composed of and where would you find it?
glucose + glucose; grain
some animals form ____ for exoskeletons
chitin
plants form cell walls from ______
cellulose
monomer of RNA
nucleic acid
parts of nucleic acid
sugar, phosphate group, and a nucleotide base
process that froms bonds between monomers
dehydration reaction
parts of amino acid
carboxyl group, amino group, functional group
a fat with one double carbon bond is:
monounsaturated
What is the same in both DNA & RNA?

a) sugar
b) phosphate
c) base
d) function
b) Phosphate
Olive oil is what type of fat?
Unsaturated
What do the monomers of all macromolecules have in common?
A carbon backbone and a functional group
Hormones are generally made of _______
proteins
Antibodies are made of ______
proteins
Enzymes are made of ______
proteins
______ bond joins amino acids together
Peptide
Which organelles are present in both prokaryotes and eukaryotes?
Ribosomes
Which organelle produces rRNA?
Nucleolus
Which organelle is responsible for protein synthesis?
Rough ER
Which organelle packages and puts the finishing touches on proteins?
Gogli body
Reads RNA to make proteins
Ribosomes
Forms carbohydrates/lipids
Smooth ER
Neutralizes/inactivates toxins in cell
Peroxisomes
Engulfs old organelles, breaking them down
lysosomes
Bind cells to other cells to form tissues
intermediate filaments
Net movement of molecules down a concentration gradient
diffusion
Engulfs specific substances into cells
receptor-mediated endocytosis
Move water across cell membranes using facilitated diffusion
Aquaporins
What are the relevant numbers for the sodium-potassium pump?
3 Na+ out, 2 K+ in
Transport against concentration gradient
Active transport
glucose and amino acids are brought in the cell through:
coupled transport
Rate of diffusion is ________ by high temperatures
increased
Rate of diffusion is ________ by large molecular size
decreased
Rate of diffusion is ________ by large concentration gradient
increased
Rate of diffusion is ________ by large surface area
increased
Channels that connect cytoplasms of adjoining cells, allowing coordinated contraction as in heart muscle
Gap junctions
Type of diffusion that requires a membrane protein
Facilitated diffusion
Adds flexibility to plasma membrane
cholesterol
Used for steroids, bile
cholesterol
Hold strands of DNA together
hydrogen bonds
Driving force of passive membrane transport
Concentration gradient
Net gain of ATP during glycolysis
2 ATP
The starting material of glycolysis
1 glucose and 2 ATP
The starting material of pyruvate oxidation
2 pyruvates
The starting material of the Kreb's Cycle
2 Acetyl Co-A, also sort of the four carbon sugar counts
End product of Kreb's Cycle
2 ATP, and back to four-carbon sugar
End product of glycolysis
2 pyruvates and 4 ATP
End product of pyruvate oxidation
2 acetyl-CoA
Where does Kreb's cycle occur?
In mitochondrial matrix
Under what conditions does fermentation occur?
Anaerobic
In what phase of mitosis do spindle fibres first start to form?
Prophase
When do sister chromatids begin to split apart?
Anaphase
In meiosis __, sister chromatids separate
II
In meiosis __, homologous pairs separate
I
The last checkpoint of the cell cycle
M Checkpoint
"On button" for cell division
Proto-oncogene
If the "Off button" is broken, causing unchecked cell division, it is due to an:
Oncogene
Crossing over occurs during:
Prophase I
Method of determining genotype of phenotypically dominant organism
Testcross