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213 Cards in this Set
- Front
- Back
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The viral reproductive cycle characterized by integration of the bacteriophage nucleic acid into the host bacterium's genome
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Lysogenic cycle
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When a virus has integrated its DNA into the host's genome, it's called a:
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prophage
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Have a thin peptidoglycan layer and stain pink
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Gram-negative bacteria
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Have a lipopolysaccharide layer
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Gram-negative bacteria
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Have a thick peptidoglycan layer and stain purple
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Gram-positive bacteria
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Protein coats that contain DNA or RNA
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Viruses
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Enzyme that converts the viral RNA to DNA, which is then integrated into the cell’s chromosome
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reverse transcriptase
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A primary connection between the nervous system and endocrine system
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Hypothalamus
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A cross between two individuals results in a ratio of 9:3:3:1 for four possible phenotypes. This is an example of a:
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Dihybrid cross
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Analogous structures in organisms are the result of…
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Convergent evolution
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A potential problem with the chromosomal theory of inheritance is that there are many more ____ that assort independently than there are ________
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traits; chromosomes
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an abnormal chromosome number
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aneuploidy
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Accidental changes in genes
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Mutations
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an incurable disorder in which some Ashkenazi Jews' brains deteriorate
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Tay-Sachs disease
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According to ________, giraffes evolved long necks because ancestral giraffes tended to stretch their necks and this neck extension was passed on to subsequent generations
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Jean-Baptiste Lamarck
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According to _______, the variation is not created by experience, but already exists when selection acts on it
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Darwin
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__________ states that species experience long periods of little or no evolutionary change (termed ____), interrupted by bursts of evolutionary change
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Punctuated equilibrium; stasis
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because the proportions of genotypes do not change from generation to generation, the genotypes are said to be in:
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Hardy-Weinberg equilibrium
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a change in a nucleotide sequence in DNA
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Mutation
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______ are generally too low to significantly alter Hardy-Weinberg proportions
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Mutation rates
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a breeder selects for the desired characteristics
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artificial selection
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a form of selection that occurs when selection acts to eliminate one extreme from an array of phenotypes
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Directional selection
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______ cell mutations don't affect gametes
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somatic
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Capsules are thick and __________ in shape
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definite, uniform
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A ____________ bacterial cell well is 80 to 90% peptidodoglycan
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Gram-positive
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A ____________ bacterial cell well is 80 to 90% peptidodoglycan
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Gram-negative
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Occurs when homologous chromosomes or sister chromatids fail to separate during meiosis
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Nondisjunction
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Features that have a similar function but different structural origin are called…
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Analogous structures
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Features that have a different form or function but similar structural origin are called…
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Homologous structures
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Homologous structures in organisms are the result of…
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Divergence
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The virus reproductive cycle where the virus enters the cell, uses the cell structures to make more viruses, then bursts open the cell to release the new viruses
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Lytic cycle
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when crossing individuals who are true-breeding for two different characters, the F1 individual that results is a:
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dihybrid
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Name the law:
the two alleles of a trait separate from each other during the formation of gametes, so that half of the gametes will carry one copy and half will carry the other copy |
Mendel’s First Law: Segregation
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Name the law:
genes located on different chromosomes are inherited independently of one another |
Mendel’s Second Law: Independent Assortment
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The chromosomal theory of inheritance was first proposed in 1902 by:
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Walter Sutton
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Experimental study of this creature by Thomas Hunt Morgan provided confirmation of the chromosomal theory of inheritance
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the fruit fly (Drosophila melanogaster)
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The vehicles of Mendelian inheritance
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chromosomes
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The mutant male fruit fly with white eyes demonstrated a __________ trait
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sex-linked
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traits assort independently because _________ assort independently
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chromosomes
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the tendency of close- together genes to segregate together
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Linkage
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the further two genes are from each other on the same chromosome, the ___ likely crossing over is to occur between them
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more
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Down syndrome is caused by having:
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an extra copy of chromosome 21
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Name chromosomal disorder: Usually taller than average but other symptoms vary
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XXX female
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nondisjunction of the X chromosome creates three possible viable conditions (name the chromosome arrangements)
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XXX, XXY and XO
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Name chromosomal disorder:
sterile male with many female characteristics and diminished mental capacity |
Klinefelter syndrome
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Name chromosomal disorder:
sterile female with webbed neck and diminished stature |
Turner syndrome
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Nondisjunction of the Y chromosome leads to ___ males
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XYY
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mutations occur only rarely and almost always result in _____ alleles
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recessive
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one can identify which relatives exhibit a trait by looking at family trees or:
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pedigree
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Pedigree key:
Circles represent _______ |
females
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Pedigree key:
Squares represent _______ |
males
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Pedigree key:
White means ______ |
unaffected
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Pedigree key:
Black means _____ |
Affected
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Pedigree key:
Half black half white means _____ |
Carrier
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People with sickle-cell anemia carry a mutated gene that produces a defective version of _______
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Hemoglobin
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Why is sickle-cell anemia more common than Tay-Sachs?
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Tay-Sachs sufferers die by age five, sickle-cell carriers have adaptive advantage
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genetic disorder caused by a dominant allele, causes progressive deterioration of brain cells
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Huntington's disease
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fetal cells from the chorion in the placenta are
removed for analysis |
Chorionic villus sampling
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when amniotic fluid
is sampled and isolated fetal cells are then grown in culture and analyzed |
Amniocentesis
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Genetic counselors look at 3 things from the cell cultures obtained from either amniocentesis or chorionic villus sampling:
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1. chromosomal karyotype
2. enzyme activity 3. genetic markers |
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most recent form of genetic counseling
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DNA screening
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procedure where parents conceiving by in vitro fertilization (aka. “test-tube babies”) can screen zygotes for potential genetic anomalies
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preimplantation screening
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large scale patterns, trends, rates of change among groups of species
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Macroevolution
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cumulative genetic changes that give rise to new species
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Microevolution
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changes that occur within a species that make that species different from its immediate ancestor
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Microevolution
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results from microevolutionary changes that increase the likelihood of survival and reproduction of particular genetic traits in a population
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adaptation
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predecessor to Darwin who proposed that evolution occurred by the inheritance of acquired characteristics
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Jean-Baptiste Lamarck
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states that evolutionary change occurs extremely slowly
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Gradualism
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the most direct evidence of macroevolution
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fossil records
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the preserved remains, tracks, or traces of once-living organisms
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fossils
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structures that have no function
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Vestigial structures
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changes in an individual gene, compared over a broad array of organisms, dated from the time of divergence
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molecular clock
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study of the properties of genes in populations
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Population genetics
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the sum of all of the genes in a population, including all alleles in all individuals
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Gene pool
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in a large population in which there is random mating, and in the absence of forces that change allele frequencies, the original genotype proportions __________ from generation to generation
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remain constant
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Different traits exist in a population in varying _______
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frequencies
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If the proportions of a genotype remain constant from generation to generation, they are in:
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Hardy-Weinberg equilibrium
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the proportion of individuals with a certain characteristic compared to an entire population
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frequency
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knowing the frequency of the phenotype, one can calculate the frequency of _____ and ____ in the population
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genotypes and alleles
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The Hardy-Weinberg equilibrium only works if the following 5 assumptions are met:
1. The size of the population is _____ 2. Individuals can mate with one another __________ 3. There is no ________ 4. There is no ________ or ______ 5. All alleles are ________ ______ from generation to generation |
1. very large or effectively infinite
2. at random 3. mutation 4. immigration or emigration 5. replaced equally |
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the frequency of heterozygote carriers for recessive genetic disorders can be estimated using:
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the Hardy-Weinberg rule
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mutations must affect the DNA of _________ or the mutation will not be passed on to offspring
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the germ cells
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no matter how rare, ______ is the ultimate source of variation in a population
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mutation
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the movement of individuals between populations
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Migration
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the magnitude of the effects of migration is based on 2 factors:
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1. proportion of migrants
2. difference in allele frequencies b/w migrants, original population |
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random changes in allele frequencies
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Genetic drift
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in small populations, the frequencies of particular alleles may be changed drastically by ________
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chance alone
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occurs when one of a few individuals migrate and become the founders of a new, isolated population at some distance from their place of origin
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founder effect
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when a population is drastically reduced in size
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bottleneck effect
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when individuals with certain genotypes mate with one another either more or less commonly than would be expected by chance
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Nonrandom mating
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choosing a mate based on, often, physical characteristics
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sexual selection
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nonrandom mating alters _______ frequencies but not ______ frequencies
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genotype; allele
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occurs if some individuals leave behind more progeny than others
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Selection
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conditions in nature determine which kinds of individuals in a population are the most fit
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natural selection
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form of selection in which both extremes from an array of phenotypes are eliminated
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Stabilizing selection
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form of selection in which the two extremes in an array of phenotypes become more common in the population
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Disruptive selection
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when the payoff in survival of heterozygotes makes up for the price in death of homozygotes
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heterozygote advantage
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Selection on color in guppies is an example of:
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disruptive selection
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The protective external covering of a prokaryotic cell is called _________ and consists of what three layers?
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Cell envelope;
– Glycocalyx – Cell wall – Cell/plasma membrane |
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Glycocalyx subdivides into:
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capsule and slime layer
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General term for structures found outside of the cell wall (extracellular)
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Glycocalyx
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Polysaccharide layer of prokaryotic cell – sticky, complex sugars
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Glcocalyx
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Functions include communication b/w cells, interaction w/ other ECMs, anchoring of cells, protection from pathogens, involved in the (human) immune response, and formation of biofilms
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Glycocalyx
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Steps in prokaryotic cell division
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DNA replication + binary fission
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Conduits of bacterial genetic transfer, and what they transmit
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Pili; plasmids
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Contributes to bacterial cell virulence by protecting it from phagocytosis and drying
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Capsule
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Protects bacterial cell from drying, promotes adherence
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Slime layer
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Protective outer layer of bacterium composed of peptidoglycan (a glycoprotein)
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Cell wall
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The bacterial cell wall is composed of (specifically):
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peptidoglycan (a glycoprotein)
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Provides a bacterium strength against osmotic pressure and determines the results of Gram's stain
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Cell wall
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Site of action of antimicrobial drugs such as penicillins
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Cell wall
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The plasma membranes of Gram-______ bacteria are encased within a porous cell wall of peptidoglycan
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positive
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In Gram-______ bacteria, the peptidoglycan layer is thin and covered by an outer layer of __________
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negative; lipopolysacharride
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Tay Sachs is caused by a defective allele on what chromosome?
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chromosome 15
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Huntington's is caused by a defective allele on what chromosome?
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chromosome 4
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Sickle cell anemia is caused by an allele on what chromosome?
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chromosome 11
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Changes in allele frequency lead to ____evolution
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microevolution
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When the same parts have different functions on different species, it's morphological _________
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morphological divergence
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When different parts have similar functions on different species, it's morphological _________
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morphological convergence
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The polysaccharide (sticky sugar) layer is what part of the cell envelope?
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Glycocalyx
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A bacterium with both a capsule and a slime layer is:
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Impossible
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Stains purple
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Gram-positive
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Stains pink
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Gram-negative
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Spherical bacterial shape
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cocci
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Rodlike bacterial shape
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bacilli
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Bacterial arrangement in pairs
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diplo
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Bacterial arrangement in chains
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Strepto
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Bacterial arrangement in bunches
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Staphylo
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Use the energy of sunlight to build organic molecules from CO2
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Photoautotrophs
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Obtain their energy by oxidizing inorganic substances
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Chemoautotrophs
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Use sunlight for energy but obtain carbon from organic
molecules produced by other organisms |
Photoheterotrophs
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Obtain both carbon atoms and energy from organic molecules
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Chemoheterotrophs
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HIV recognizes ___ surface marker on macrophages and,
later, T cells |
CD4
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What marks onset of AIDS?
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Infection and destruction of T cells
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Pili are composed of:
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Pilin protein
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Sex pili are also called:
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conjugation bridge
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Bacterium with one flagellum
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Monotrichous
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Bacterium with multiple flagella located at the same spot on the bacterium's surface
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Lophotrichous
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Bacterium with flagella located on opposite sides of the bacterium's surface
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Amphitrichous (technically only one on each side, but that's not what diagram says)
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Bacteria with flagella projecting in all directions
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Peritrichous
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Thick walled resistant body around genetic material
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Endospores
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Allows bacteria to resist environmental stress (extreme temps, drying, radiation, chemicals)
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Endospores
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Bacteria with endospores are in a _______ state
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dormant
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Can be free-floating or integrated into bacterial chromosome
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Plasmid
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Extra-chromosomal genetic element that may confer protective traits to bacteria
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Plasmid
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Changes in allele frequency leading to microevolution can be due to:
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natural selection or genetic drift
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when some individuals leave behind more progeny than others
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Selection
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If a macromolecule has an R group it is a ______
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protein
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sucrose is a combination of
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glucose + fructose
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Monosaccharide or disaccharide:
Galactose |
Monosaccharide
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Monosaccharide or disaccharide:
Lactose |
disaccharide
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Monosaccharide or disaccharide:
Glucose |
Monosaccharide
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Monosaccharide or disaccharide:
Maltose |
disaccharide
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Monosaccharide or disaccharide:
Fructose |
Monosaccharide
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Monosaccharide or disaccharide:
Sucrose |
disaccharide
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What is maltose composed of and where would you find it?
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glucose + glucose; grain
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some animals form ____ for exoskeletons
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chitin
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plants form cell walls from ______
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cellulose
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monomer of RNA
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nucleic acid
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parts of nucleic acid
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sugar, phosphate group, and a nucleotide base
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process that froms bonds between monomers
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dehydration reaction
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parts of amino acid
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carboxyl group, amino group, functional group
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a fat with one double carbon bond is:
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monounsaturated
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What is the same in both DNA & RNA?
a) sugar b) phosphate c) base d) function |
b) Phosphate
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Olive oil is what type of fat?
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Unsaturated
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What do the monomers of all macromolecules have in common?
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A carbon backbone and a functional group
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Hormones are generally made of _______
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proteins
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Antibodies are made of ______
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proteins
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Enzymes are made of ______
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proteins
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______ bond joins amino acids together
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Peptide
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Which organelles are present in both prokaryotes and eukaryotes?
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Ribosomes
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Which organelle produces rRNA?
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Nucleolus
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Which organelle is responsible for protein synthesis?
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Rough ER
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Which organelle packages and puts the finishing touches on proteins?
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Gogli body
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Reads RNA to make proteins
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Ribosomes
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Forms carbohydrates/lipids
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Smooth ER
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Neutralizes/inactivates toxins in cell
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Peroxisomes
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Engulfs old organelles, breaking them down
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lysosomes
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Bind cells to other cells to form tissues
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intermediate filaments
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Net movement of molecules down a concentration gradient
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diffusion
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Engulfs specific substances into cells
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receptor-mediated endocytosis
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Move water across cell membranes using facilitated diffusion
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Aquaporins
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What are the relevant numbers for the sodium-potassium pump?
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3 Na+ out, 2 K+ in
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Transport against concentration gradient
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Active transport
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glucose and amino acids are brought in the cell through:
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coupled transport
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Rate of diffusion is ________ by high temperatures
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increased
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Rate of diffusion is ________ by large molecular size
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decreased
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Rate of diffusion is ________ by large concentration gradient
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increased
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Rate of diffusion is ________ by large surface area
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increased
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Channels that connect cytoplasms of adjoining cells, allowing coordinated contraction as in heart muscle
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Gap junctions
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Type of diffusion that requires a membrane protein
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Facilitated diffusion
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Adds flexibility to plasma membrane
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cholesterol
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Used for steroids, bile
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cholesterol
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Hold strands of DNA together
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hydrogen bonds
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Driving force of passive membrane transport
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Concentration gradient
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Net gain of ATP during glycolysis
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2 ATP
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The starting material of glycolysis
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1 glucose and 2 ATP
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The starting material of pyruvate oxidation
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2 pyruvates
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The starting material of the Kreb's Cycle
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2 Acetyl Co-A, also sort of the four carbon sugar counts
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End product of Kreb's Cycle
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2 ATP, and back to four-carbon sugar
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End product of glycolysis
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2 pyruvates and 4 ATP
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End product of pyruvate oxidation
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2 acetyl-CoA
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Where does Kreb's cycle occur?
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In mitochondrial matrix
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Under what conditions does fermentation occur?
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Anaerobic
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In what phase of mitosis do spindle fibres first start to form?
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Prophase
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When do sister chromatids begin to split apart?
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Anaphase
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In meiosis __, sister chromatids separate
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II
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In meiosis __, homologous pairs separate
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I
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The last checkpoint of the cell cycle
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M Checkpoint
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"On button" for cell division
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Proto-oncogene
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If the "Off button" is broken, causing unchecked cell division, it is due to an:
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Oncogene
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Crossing over occurs during:
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Prophase I
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Method of determining genotype of phenotypically dominant organism
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Testcross
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