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49 Cards in this Set
- Front
- Back
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homeostais
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the process by which the body's substances and characteristics, such as temperature and glucose level are maintained at their optimal level
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ingestive behavior
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eating or drinking
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system variable
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a variable that is controlled by a regulatory mechanism; for example, temperature in a heating system
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set point
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the optimal value of the system variable in a regulatory mechanism
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detector
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in a regulatory process, a mechanism that signals when the system variable deviates from its set point
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correctional mechanism
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in a regulatory process, the mechanism that is capable of changing the value of the system variable
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negative feedback
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a process whereby the effect produced by an action serves to diminsih or terminate that action; a characteristic of regulatory systems
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satiety mechansim
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a brain mechanism that causes cessation of hunger or thirst, produced by adequate an available supplies of nutrients or water
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extracellular fluid
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all body fluids outside cells, intersitial fluid, blood plasma, and cerebrospinal fluid.
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intersitial fluid
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the fluid that bathes the cells, filling the space between the cells, the interstices
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isotonic
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equal in osmotic pressure to the contents of a cell. A cell placed in an isotonic solution neither gains nor loses water
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hypertonic
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the characteristic of a solution that contains enough solute that it will draw water out of a cell placed in it, through the process of osmosis
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hypotonic
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the characteristic of a solution that contains so little solute that a cell placed in it will absorb water, through the process of osmosis
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hypovolemia
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reduction in the volume of the intravascular fluid
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osmometic thirst
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thirst produced by an increase in the osmotic pressure of the interstitial fluid relative to the intercellular fluid, thus producing cellular dehydration
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osmoreceptor
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a neuron that detects changes in the solute concentration of the interstitital fluid that surrounds it
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volumetric thirst
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thirst produced by hypovolemia
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renin
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a hormone secreted by the kidneys that causes the conversion of angiotensinogen in the blood into angiotensin
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angiotensin
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a peptide hormone that constricts blood vessels, causes the retention of sodium and water, and produces thirst and a salt appetite
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subfornical organ (SFO)
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a small organ located in the confluence of the lateral ventriles, attached to the underside of the fornix; contains neurons that detect the presence of angiotensin in the blood and excite neural circuits that initiate drinking
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median preoptic nucleus
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a small nucleus stiuated around the front of the anterior commissure; plays a role in thrist stimulated by angiotensin
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glycogen
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a polysacchride often referred to as animal strach; stored in lever and muscle; constitutes the short-term store of nutrients
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insulin
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a pancreatic hormone that facilitates entry of glucose and amino acids into the cell, conversion of glucose not glycogen, and transport fats into adipose tissue
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glucagon
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a pancreatic hormone that promotes the conversion of liver glycogen into glucose
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triglyceride
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the form of fat storage in adipose cells; consists of a molecule of glycerol joined with three fatty acids.
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glycerol
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a substance (also called glycerine) derived from the breakdown of triglycerides, along with fatty acids; can be converted by the liver into glucose
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fatty acid
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a substance derived from the breakdown of triglycerides, along with glycerol; can be metablized by most cells of the body except for the brain.
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fasting phase
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the phase of metablism during which nutrients are not available from the digestive system; glucose, amino acids, and fatty acids are derived from glycogen, protein, and adipose tissue during this phase
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absorptive phase
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the phase of metabolism during which nutrients are absorbed from the digestive system; glucose and amino acids constitute the principal source of energy for cells durigng this phase, and excess nutrients are stored in adipose tissue in the form of triglycerides
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ghrelin
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a peptide hormone released by the stomach that increases eating, also produced by neurons in the brain
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duodenum
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the first portion of the small intestine, attached directly to the stomach
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glucoprivation
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a dramatic fall in the level of glucose available to cells; can be caused by a fall in the blood level of glucose or by drugs that inhibit glucose metablism
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lipoprivation
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a dramatic fall in the level of fatty acids available to cells; usually caused by drugs that inhibit fatty acid metabolism
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hepatic protal vein
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the vein that transports blood from the digestive system to the liver
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cholecystokinin (CCK)
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a hormone secreted by the duodenum that regulates gastric motility and causes the gallbladder to contract; appears to provide a satiety signal transmitted to the brain through the vagus nerve
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peptide YY 3-36 (PYY)
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a peptide released by the gastrointestinal system after a meal in amounts proportional to the size of the meal
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ob mouse
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a strain of mice whose obesity and low metabolic rate are caused by a mutation the prevents the production of leptin
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leptin
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a hormone secreted by adipose tissue; decreases food intake and increases metabolic rae, primarily by inhibiting NPY-secreting neurons in the arcuate nucleus.
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decerebration
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a surgical procedure that serves the brain stem, disconecting the hindbrain form the forebrain
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melanin-concentrating hormone (MCH)
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one of two peptide neurotransmitters found in a system of latera hypothalamic neurons that stimulate appetite and reduce metabolic rate
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orexin
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one of two peptide neurotransmitters found in a ystem of lateral hypothalmic neurons that stimulate appedite and reduce metabolic rate. also called hypocretin
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neuropeptide Y (NPY)
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a peptide neurotransmiter dound in a system of neurons of the arcuate nucleus that stimulate feeding, insulin and glucorticoid secretion, decrease the breakdown of triglycerides, and decrease body temperature
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arcuate nucleus
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a nucleus in the base of the hypothalamus that controls secretions of the anterior pituitary gland; contains NPY-secreting neurons involved in feeding and control of metabolism
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paraventricular nucleus (PVN)
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a nucleus of the hypothalamus located adjacent tot he dorsal third ventricle; contains neurons involved in control of the autonomic nervous system and the posterior pituitary gland
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agouti-related protein (AGRP)
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a neuropeptide that acts as an antagonist at MC-4 receptors and increases eating
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CART
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cocain-and amphetamine-related transcript; a peptide neurotransmitter found in a system of neurons of the arcuate nucleus that inhibit feeding
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a-melanocyte-stimulating hormone (a-MSH)
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a neuropeptide that acts as an agonist at MC-4 receptors and inhibits eating
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meanocortin-4 receptor (MC_4R)
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a receptor found in the brain that binds with a-MSH and agouti-related protein; plays a role in conrol of appetite.
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uncoupling protein (UCP)
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a mitochrondrial protein that facilitates the conversion of nutrients into heat
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