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5 Cards in this Set
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What's the difference between lymphoma and leukemia?
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lymphoma = lymph node origin (Hodgkin's vs. Non-hodgkins)
leukemia = bone marrow origin (AML/CML/ALL/CLL) |
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What is the difference between chronic and acute leukemias?
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acute vs. chronic is a histological diagnosis based on the presence or absence of blast (immature cells).
acute = immature = more aggressive course |
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What is the most common leukemia?
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CLL (15,000 cases annually)
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What are the clinical signs of leukemia?
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Acute leukemias tend to have symptoms (as listed below), but chronic leukemias tend to be asymptomatic
* Constitutional symptoms: fever, malaise, dyspnea * Bleeding: usually related to thrombocytopenia * Infection: can be as dramatic as overwhelming sepsis * Bone pain: from the expanding leukemic cell mass within the marrow * Neurologic symptoms: ranging from headache to seizures and cranial nerve palsies and caused by leukemic cell infiltration of the meninges |
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What's the difference between myeloid and lymphoid?
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the cell line:
myeloid = PMNs, monocytes and macrophages, eosinophils, basophils, mast cells. Erythrocytes and platelets/megakaryocytes. Lymphoid = B/T cells, NK cells |
