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3 Cards in this Set
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- Back
- 3rd side (hint)
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HFE mutation
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"High Fe" = hematochromatosis
protein on basolateral membrane of SI intestinal crypt cells compelxes with β2 microglobulin and binds transferrin receptor to regulat endocytosis of transferrin/iron intracellular [iron] ≈ systemic iron → suppresses iron uptke mutation = hematochromatosis Liver cirrhosis and hepatocellular carcinoma are the end stage |
#pathology #hematology |
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Hematochromatosis
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HFE "High Fe" Mutation
protein on basolateral membrane of SI intestinal crypt cells compelxes with β2 microglobulin and binds transferrin receptor to regulat endocytosis of transferrin/iron intracellular [iron] ≈ systemic iron → suppresses iron uptke mutation = hematochromatosis Liver cirrhosis and hepatocellular carcinoma are the end stage |
#pathology #hematology |
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Deciduized Endometrium
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ie pregnant or acting like it's pregnant
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#physiology #reproductive |
