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What is CSF?
It is a clear colorless liquid that fills the ventricles and canals of the CNS and bathes its external surface.
About how much CSF is produced every day?
It produces about 500 mL per day, but the fluid is constantly reabsorbed at the same rate and only about 100-160 mL is normally present at any one time.
About 40% of it is formed in the subarachnoid space external to the brain. True/False
True. About 30% is formed by the general ependymal lining and 30% by the choroid plexus.
How does CSF production begin?
It begins with the filtration of blood plasma through the capillaries of the brain. Ependymal cells modify the filtrate.
Is sodium and chloride normally found in the CSF?
Yes. The CSF has more sodium and chloride than blood plasma, but less potassium, calcium and glucose, and very little protein.
What are the three major functions of CSF?
Buoyancy, Protection and Chemical stability.
Is the brain more dense than CSF.
Not really. They are similar in density,and the brain can float in CSF.
It hangs from arachnoid meninx.
App. how heavy is the brain?
It weighs about 1500 g, but when suspended in CSF, its weight is only 50g. If the brain rested heavily on the floor of the cranium, the pressure would irreparably damage the nervous tissue.
How does the CSF protect the brain?
It protects the brain from striking the cranium when the head is jolted, though this is still possible depending on the gravity of the trauma.
This may be a finding in shaken child syndrome.
How is chemical stability conferred to the brain with CSF?
The flow of CSF rinses metabolic wastes from the nervous tissue and homeostatically regulates its chemical environment.
Slight changes in CSF composition can result in malfunctions of the nervous system. True/False
True. A high glycine concentration disrupts the control of body temperature and blood pressure, and a high pH results in dizziness and fainting.