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12 Cards in this Set
- Front
- Back
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Rejection Grading
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0R
1R 2R 4R |
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0R
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No Rejection = 1990 (Grade 0)
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1R Mild 2004
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Interstitial and/or perivascular infiltrates with up to 1 focus of myocardial damage
1990 = 1A,1B, 2 (myocyte damage) |
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2R moderate 2004
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2 or more foci of infiltrate with association w/myocyte damage
1990 Grade 3 A -focal |
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3R Severe
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Diffuse infiltrate w/multifocal myocyte damage, +/- edema, hemorrhage, vasculitis
1990 Grade 3B, 4 |
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Hyperacute rejection
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hemorrhage , edema, plt aggregates in blood vessels, with time polys.
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Acute rejection
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lymphocytes, macrophages, eos
No neuts No plasma cells (Quilty or PTLD) |
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Eos
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Toxo, CMV, drug rxn
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Acute antibody mediated rejection
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capillary injury, endothelial swelling & intravascular macrophages
Edema, hemorrhage, neutrophils near capillaries, thrombi & myocyte necrosis |
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Quilty Lesion
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Dense lymphocytes within the endocardium,
b+T cells cyclosporin, one piece of tissue |
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Endocarditis
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Bacterial-friable vegetations
Marantic - small attached to lines of closure-valve surface Limban - Sacks - SLE - both surfaces - T>M>P>A |
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RHD
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RF - Grp A strep (Beta-hemolytic)
Aschoff Nodules-Aschoff giant cell Anitschkow cells - mononuclear histiocytes - arranged in a palasade around the center of a granuloma Mitral stenosis - fishmouth |