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14 Cards in this Set
- Front
- Back
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WHAT PATHWAY DOES C1 INHIBITOR EFFECT
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classical
soluble protein |
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what pathway does Factor H effect
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alternative
soluble protein |
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what pathway does Factor I effect
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classical,alternative
soluble protein |
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what pathway does DAF effect
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classical, alternative
membrane bound |
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what pathway does CR1 effect
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classical, alternative
membrane bound |
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what does C1 inh inhibit
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inhibits formation of C1qrs and bradykinin/C2 kinin (C2b)
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a deficiency in hereditary angioedema
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C1inh deficiency
angiodema occurs b/c C1qrs is not inhibited |
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what does Factor/H/I inhibit
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Factor H binds C3b and Factor I cleaves it
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deficiency causes C3 consumption
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factor H/I
leads to accelerated formation of C3 convertase |
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wha does CR1 inhibit
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binds C3b and prevents C3b from combining w/ factor B
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what serves as a cofactor for C3b cleavage by Factor I
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Factor H and CR1
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what inhibits C3 convertase formation
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Factor H/I
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what does DAF do
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asselerates dissociation of C3 convertase
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what deficiency causes paroxymal nocturnal hemoglobinuria (PNH)
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DAF deficiency
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