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8 Cards in this Set
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- Back
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What is the most common generalized lympadenopathy in individuals >60?
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CLL
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What is the most common overall leukemia?
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CLL
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What is the pathogenesis of Chronic Lympocytic Leukemia?
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Neoplastic disorder of virgin B-cells( b-cells that can't differentiate
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What are the clinical findings of CLL?
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Lymphadenopathy
Metastatic sites similar to AML Increased incidence of immune hemolytic anemia: Warm (IgG) and Cold (IgM) |
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What are the Lab Findings of CLL
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WBC: 15,000-200,000/uL
---Lympho less than 10% ----Neutropenia ----Smudge cells ( Fragile leukocytes) |
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What type of anemia is found in CLL?
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Normocytic ~50% and thrombocytopenia ~40%
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What are the bone marrow findings for CLL?
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Bone marrow is usually replaced with neoplasitc B-cells
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What is commonly found with the immunoglobins?
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hypogammaglobulienemia
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