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15 Cards in this Set

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What are the most impt. causative agents of acute meningitis?
**Almost always bacterial***
Neisseria Meningitidis, Haemophilu influenzae type b, Strep. Pneum., Group B Strep (S. Agalact.), Listeria Monocytogenes
What are the most common causes of transverse myelitus?
**Rare**
HSV-2, ENV
What is the most common cause of myelitis? Which is the most fatal form?
Polio, Bulbar Polio
What are the most common causative agents of brain abscesses?
Staph, Strep, Oral Flora (including anerobes), Enterobacteriaceae
What is PML and what causes it?
Progressive Multifocal Demyelinating disease, JC virus
What is SSPE and what causes it?
Subacute sclerosing panencephalitus, measles virus
What are the most common causes of encephalitis in the U.S.
**Almost always viral**
1.Enteroviruses
2.La Crosse Virus
3.HSV
4.West Nile Virus
5. St. Louis Virus
Pneumonic: Encephalitis is Lame bc Head Wounds Suck
What are the most common causative agents of bacterial meningitis?
1. Strep Pneum **Most Freq in Adults**
2.Neisseria Meningitidis **Most freq. in children & Young adults** 3.Enteric Gram Neg. Rods
4.Group B Strep.
5.Listeria Monocytogenes
6.Haemophilus Influenzae B
What are the 2 forms of spore-forming bacteria that are medically important?
**Both are Gram-positive rods**
1.Bacillus
2. Clostridium
What fungus is the most frequent cause of fungal meningitis?
Cryptococcus
What is fluconazoles MOA? What CNS pathogen is it used for?
Blocks conversion of lanosterol to ergosterol. Used for maintenance therapy of Cryptococcus neoformans
What does PAM stand for and what is its causative agent?
Primary Amebic Meningioencephalitis; Naegleria Fowleri
What is a positive Brudzinski sign?
Flexion of the hips & knees when the neck is flexed in a supine position
What is a positive Kernig Sign?
Resistance to extending the knee when the hips & knees are flexed
What is the only infectious agent that causes meningitis that produces an abnormal sense of smell?
Naegleria fowleri --> PAM