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19 Cards in this Set

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  • Back
cognition
mental process of knowing, aspect of awareness, perception, reason, and judgement
what is delirium?
mental disturabance marked by clouding of consciousness
reduced awarenes of surroundings and inability to sustain attention often with restlessness
what does delirium indicate?
medical emergency
it is a secondary symptom of things that could be fatal
causes of delirium?
fever
alcohol withdrawal
metabolic condiions
infections
toxicity
drugs
entoxication
what is dementia?
patient is alert but there is deterioration sufficently severe to interfere with social occupational requirements, often insideous onset, but can be sudden
what is characterized by dementai?
gradually interfere with daily living activities that are approproate for age and background
what are the defecits in dementia?
memory loss
loss of creativity
loss of reasoning
dementia can incite episodes of what?
delirium
diagnosis of dementia requires?
complete history
complete neurological exam
b12, thyroid
MRI
what is a the main cause of dementia?
alzheimers/parkinsons
what is the most common cause of dementia in young people?
HIV
what are some causes of dementia?
HIV
Alzheimers
parkinson
lewybody dementia
Creutzjacob prion disease
vascular cognative impairment
depreesion
korsakoff
b12 deficiency
hydrocephalus
syphilus
carbon monoxide
hematoma
... lots
cause of alzheimer
amyloid beta deposit in plaques and tangles
what are the 4 genes for alzheimer
autosomal dominant
chromosome 21-APP
chromosome 14-presenilin 1
chromosome 1- presenlin 2

codominant
chromosome 19- apolipoprotien
what protein folding diseases are with what protein?
alzheimer- amyloid beta
frontotemporal dementai, - tau
cretzfedt jacab - PrP
parkinsons disease alpha synuclein
huntingtons disease - huntingtin
motor neuron disease - TDP-43
what is a common feature in several dementai disease?
abnormal folding of beta protein
what is the toxic by product in alzheimers?
the oligo plaque of beta not the endign polymer
alzyheimer disease progression lasts how long?
several decades, but dementia doesnt begin till last few years
what is seen on scans for alzheimers?
regional, asymetric cerebral atrophy