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9 Cards in this Set

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CYANIDE ANTIDOTE KIT
Class/ MOA
Class
Antidote
Mechanism of Action
Amyl Nitrite: affinity for cyanide ions; reacts with hemoglobin to form methemoglobin
(low toxicity)
Sodium Nitrite: same as amyl nitrite
Sodium Thiosulfate: produces thiocyanate, which is then excreted
CYANIDE ANTIDOTE KIT
I
Indications
Cyanide or hydrocyanic acid poisoning
CYANIDE ANTIDOTE KIT
CI
Contraindications
Not applicable
CYANIDE ANTIDOTE KIT
AR
Adverse reactions
Excessive doses of amyl nitrite and sodium nitrite can produce severe, life-threatening
methemoglobinemia. Use only recommended doses.
CYANIDE ANTIDOTE KIT
DI
Drug Interactions
None
CYANIDE ANTIDOTE KIT
how supplied
How supplied
Amyl nitrite: in pledgettes similar to ammonia capsules.
CYANIDE ANTIDOTE KIT
Does and administration
Dosage and administration
Adult: Amyl nitrite: breathe 30 seconds out of every minute. Sodium Thiosulfate
and sodium nitrite: IV per antidote kit directions.
Pediatric: Same as adult.
CYANIDE ANTIDOTE KIT
DOA
Duration of Action
Variable.
CYANIDE ANTIDOTE KIT
specials
Special Considerations
Cyanide poisoning must be recognized quickly and treated quickly; if pulse persists,
even in presence of apnea, prognosis is good with treatment. The antidote kit must
be used in conjunction with administration of oxygen.