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5 Cards in this Set
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low iron does what to virulence genes
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++ expression
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phase variation in salmonella typhimurium
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involves rapid reversible switching in synthesis of two alternative flagellar antigens (H1 and H2).
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what is the molecular switch that determine which flagellar gene will be transcribed in phase switching
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invertible segment of DNA in the promotor of the H2 gene
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neisseria gonorrhoea phase variation involves
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alternation between antigenic forms of pili on cell surface
each strain of gonococcus has copy of pilin structural gene plus many silent genes. recombinatorial exchange between the expresed and non-expressed copy of pili genes --> new pilin gene |
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mechanisms of genetic variation
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-spontaneous mutation
-recombination -acquisition of new DNA segments |
