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22 Cards in this Set

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  • Back
old lady, Jewish, begins in mouth
(+) Nikolsky's
blistering w/ split low in epidermis
pemphigus vulgaris
onset like pimple
SEVERE PAIN
high WBC, high T
crepitus, doughy to palpation
air on XR
necrotizing faciitis
what is the MC cause of necrotizing faciitis?
what predisposes?
GAS (group A strep)

DM, PVD, trauma
diffuse progressive rash
malaise, fever
PMH atopic eczema
diffuse tense vesicles w/ erythema halo
lymphadenopathy, fever, tachycardia
kaposi's varicelliform eruption (eczema herpeticum)
what is kaposi's varicelliform eruption?
aka eczema herpeticum
secondary infection of atopic eczema, usually HSV
h/o psoriasis
multiple erythematous scaled plaques
lymphadenopathy
mycosis fungoides
cutaneous T-cell lymphoma
males
indurated
mycosis fungoides
chills, fever, malaise, MOUTH ulcers
PMH: "spider bites"
mult blistering lesions
onset as erythematous sheets that desquamate w/ minimal contact
SJS
immune complex-mediated hypersensitivity rxn
causes: drugs & infection
(+) Nikolsky's
early targetoid
SJS
what are the etiological agents in SJS?
sulfonamides, amino-PCN's, cephalosporins, phenobarbital, carbamazepine, calproic acid, allopurinol

mycoplasma pneumonia, yersinia, herpes
what is the Tx for SJS?
fluids, burn unit, NO SILVADENE/ SULFUR, no corticosteroids, give Ig
what is the calculation for fluid administration for SJS?
4x(%burn) x (wt in kg) = cc's to give in 52hrs, but give first 1/2 in first 8 hrs
chills, malaise, diffuse peeling rash (>30%)
PMH: mult UTIs
TEN (toxic epidermal necrolysis)
(+) Nikolsky's
fever, leukoplakia
confluent erythema
outer layer epidermis separates form basal
drug-induced
TEN
deep swelling
face, distal extremities
acquired form assoc w/ urticaria
no pruritis
angioedema
how do ACEI's cause angioedema?
angiotensin 2 decreased, decreasing metabolism of [thus increasing] bradykinin which vasodilates and increases permeability; fluid then goes into tissues
what is the Tx for angioedema?
EPI, antihistamines, corticosteroids
purpura on infant
immune deficient (on Abx or recent infection/ fever)
meningicoccal sepsis
what is the Tx of meningicoccal sepsis?
Abx, fluids, PICU
Asx, nonpruritic lesion
raised, dark ring around it
scalp
FHx risk factor
malignant melanoma
pale, afebrile, fatigued pt
spots on tibia, mouth
low PLT count (N = 100k), predominance of blasts
acute lymphocytic leukemia
what is the MC childhood malignancy in US?
leukemia; 75% lymphoblastic