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55 Cards in this Set
- Front
- Back
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describe the breast as a modified tissue
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is a modified area of skin with speciliased sweat glands
capable of producing nutritional secretions under hormonal influence |
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what forms from the downgrowth of skin when forming breast tissue?
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epithelial pit and then a lactiferous duct
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what is the milk line
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a line down the body where accessory nipples may develop
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what 2 cells are found in the epidermis?
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keratocytes - produce keratin
melanocytes: produce melanin |
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what could a downgrowth of skin turn into?
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sweat gland
hair follicle sebacious gland apocrine gland |
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which type of gland is modified to make breast tisuse
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sweat gland
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why is the skin colour of the nipple important?
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a baby can recognise the nipple
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describe a typical sweat gland
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lumen with cells lining it
mypoepithelial cells around the outside |
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what is the difference between a sweat gland and a lactiferous duct
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lactiferous duct is stratified columnar cells
also has myoepithelial cells around it |
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describe the anatomy of the breast`
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2nd - 6th ribs
over pec major 12 - 20 lobes, with lobules each lobe has lactiferous duct which opens into a ring septa between lobes |
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what separates the lobes of a breast?
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septa
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how are septa attached to the skin?
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Coopers suspensory ligaments
fibrocollagenous bands |
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what is a mammary duct?
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an extralobular duct coming from a lactiferous dinus
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describe, from out to in, the different ducts of the breasts
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lactiferous duct, lactiferous sinus/ampulla, mamaary duct (extralobular duct), terminal intralobular duct, terminal ductule
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which ducts transform into alveoli during and when do they do this?
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terminal ductules
at pregnancy |
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describe the areola
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an area of pigmentation
sebacious glands raised area pressure receptors |
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what surrounds lactiferous ducts / sinuses?
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muscle bundles
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how many lobes in a breast?
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12 - 20
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describe breast tissue in an infant / neonate?
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simple ductal system
no alveoli similar in males and females develops ductal system in 3rd trimester |
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describe breast tissue in puberty
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influence of oestrogen and progesteorne
increase in fat and collagenous tisuse branching of ductal system |
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what happens to fetal breast tissue?
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subject to high hormone levels
grows and retracts may influence risk of breats cancer |
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what is resting breast tissue?
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breast tissue between babies or at menopause
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what are the cyclic changes a womann may experience in brast tissue?
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increase in size and tenderness premenstrually
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do males get a ductal system?
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yes
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what is found in the lumen of an adult breast?
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keratin plug
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what does the lactiferous duct usualyl contain?
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proteinacious sercretion and cellular debris
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what is the role of progesterone in pregnancy?
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maintains endothelium
prevents ovulation stimulates breast development inhibits immune rejection of embryo |
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what is the role of estrogens in pregnancy
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relaxation of pubis symphysis
proliferation of breast role in partuirition - E/P ratio |
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descrive breast tissue in pregnancy?
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switch from ductule to alveolar system
secretion distends alveolar lumen oestrogen, progesterone and prolacting all affect tissue vacuoles and fat droplets form increase in vascularity increasing lipid rich protein secretions - not true milk |
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what is the difference between alveoli and terminal ductules?
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lumen distended iwth secretion
more complex and branched secretory |
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in osmium tetraoxide, what colour is protein?
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pink
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in osmium tetraoxide, what colour is fat?
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black
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how is fat synthesized and secreted?
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by SER
passes in membrane bound droplets pinched off, released into lumen as droplet |
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how is protein released?
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exocytosis - as free protein
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which receptors must be activated for milk secretion to occur?
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prolacting
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what are the characteristics of resting breast
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alveoli still distinguisable
evidence of atrophy hypoxia of alveoli has caused involution - return to ductal system |
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what hormone level change causes lactation to occur?
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drop in oestrogen and progesterone
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what happens to alveoli when they begin to lactate?
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become enlarged
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describe the suckling reflex?
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baby orders next meal when suckling
stimulates ant. pituitary to release prolacting acts on cells to increase milk production |
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what is the milk ejection reflex?
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let down reflex
suckling stimulates oxytocin production from hypothalamu and release from pituitary stimulate muscle contraction - peristalsis |
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what stimulates the milk ejection reflex?
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sucking
when lactation established, can be just baby's cry |
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what is the MER turned down by?
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anxiety / stress
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describe colustrum
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breast milk in 1st week
high protein content high IgG content high levels of fat soluble vitamins |
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describe transitional millk
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2nd and 3rd week
higher calories less IgG fat and protein lactose water soluble vitamins |
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describe mature milke
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high water, fat and carbohydrate
lactose vitamins A and D |
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what is lactose important for?
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encourages lactobacillus - decrease pathogenic bacteria
galactose: for myelin sheath |
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what imunoglobulins are in breast milk?
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secretory IgA (most)
IgG |
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what is the immunological advantage of breast feeing?
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protection agains otitis media, sepsis, meningitis, Gi and respiratory infections, allergies
secretory IgA: antiviral, antibiotic, antigenic inhibition |
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what are the functions of IgA
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antiviral
antibiotic antigenic inhibition |
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what is nutrient sensing?
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when baby senses nutrional environment
affects metabolic programming mismatch can cause CV risk |
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what are the three main advantages of breast feeding?
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immunological
nutrient sensing psychosocial |
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describe disadvantages of breast feeding?
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1) drugs and alcohol passed on
2) diseases eg AIDS 3) jaundice from breast milk 4) mothers aversion / physical / mental state |
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describe post partuiritional behaviour?
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social, clingy, need for contact, warmth, comfort and food
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what is weaning behaviour
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gradual gain of independance
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what is gestational preparatory behaviour:
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nesting
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