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74 Cards in this Set

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What type of antidiabetic drug is a Biguanide derivative?
Metformin (Glucophage)
What type of Diabetes is Metformin used to control?
T2DM
What mechanism does Metformin use to control hyperglycemia?
decreases intenstinal absorption of glucose and improves insulin sensitivity.
What major drug interaction does metformin have?
antibiotics (Keflex)
What is the brand name for Metformin?
Glucophage
What type of antidiabetic drug is a Meglitinide derivative?
Repaglinide (Prandin)
What type of Diabetes is Repaglinide (Prandin) used to control?
T2DM
What mechanism does Repaglinide (Prandin) use to control hyperglycemia?
increased insulin release from pancreatic beta cells.
What major drug interaction does Repaglinide (Prandin)have?
antibiotics, antifungals, NSAIDs, Pain meds
What is the brand name for Repaglinide?
Prandin
What type of antidiabetic drug is a Sulfonylureas second generation agent?
Glimepiride (Amaryl)
What type of Diabetes is Glimepiride (Amaryl)used to control?
T2DM
What mechanism does Glimepiride (Amaryl) use to control hyperglycemia?
increased insulin release from pancreatic beta cells, reduces glucose output from liver
What major drug interaction does Glimepiride (Amaryl) have?
antibiotics, antifungals, NSAIDs, Pain meds
What is the brand name for Glimepiride?
(Amaryl)
What type of antidiabetic drug is a Thiazolidinedione agent?
Rosiglitazone (Avandia)
What type of Diabetes is Rosiglitazone (Avandia) used to control?
T2DM
What mechanism does Rosiglitazone (Avandia) use to control hyperglycemia?
lowers blood glucose by improving target cell response, with no insulin increase.
What major drug interaction does Rosiglitazone (Avandia) have?
Pain meds (Celebrex)
What is the brand name for Rosiglitazone?
Avandia
What type of antidiabetic drug is a alpha-glucosidase inhibitor?
Miglitol (Glyset)
What type of Diabetes is Miglitol (Glyset) used to control?
T2DM
What mechanism does Miglitol (Glyset) use to control hyperglycemia?
delayed glucose absorption
What major drug interaction does Miglitol (Glyset) have?
no major interactions
What is the brand name for Miglitol?
(Glyset)
What type of antidiabetic drug is a Dipeptidyl Peptidase IV (DPP-IV) Inhibitor?
Sitagliptin (Januvia)
What type of Diabetes is Sitagliptin (Januvia) used to control?
T2DM
What mechanism does Sitagliptin (Januvia) use to control hyperglycemia?
increased insulin levels, and decreased glucogen levels in circulation
What major drug interaction does Sitagliptin (Januvia) have?
Antibiotics (Biaxin, erythromycin) and antifungals (sproronax)
What is the brand name for Sitagliptin?
Januvia
What type of diabetic drug is an intermediate acting insulin?
NPH Insulin (Humulin)
What type of Diabetes is NPH Insulin (Humulin) used to control?
T1DM & T2DM
What mechanism does NPH Insulin (Humulin)use to control hyperglycemia?
exogenous insulin to facilitate glucose passage into liver, skeletal muscle and adipose tissues
What major drug interaction does NPH Insulin (Humulin)?
antibiotics and NSAIDs
What is the brand name for NPH Insulin?
Humulin
What type of diabetic drug is a long acting insulin?
Insulin Glargine (Lantus)
What type of Diabetes is Insulin Glargine (Lantus )used to control?
T1DM
What mechanism does Insulin Glargine (Lantus) use to control hyperglycemia?
long acting exogenous insulin to facilitate glucose passage into liver, skeletal muscle and adipose tissues
What major drug interaction does Insulin Glargine (Lantus) have?
antibiotics, NSAIDs, and aspirin
What is the brand name for Insulin Glargine?
Lantus
What type of pulmonary drug is a mucolytic antidote?
Acetylcysteine (Mucomyst)
What type of pulmonary complication is Acetylcysteine (Mucomyst) used to control?
mucolytic therapy in patients with abnormal or viscid mucous secretions in acute and chronic broncho-pulmonary diseases
What mechanism does Acetylcysteine (Mucomyst) use to control broncho-pulmonary diseases?
splits the linkage (disulfide bonds) of mucoproteins, reducing the viscosity of pulmonary secretions
What major drug interaction does Acetylcysteine (Mucomyst) have?
no major interactions
What is the brand name for Acetylcysteine?
Mucomyst
What type of pulmonary drug is a anticholinergic bronchodilating agent?
Ipratropium (Atrovent)
What type of pulmonary complication is Ipratropium (Atrovent) used to control?
blocks smooth muscle contraction during brochospamic episodes
What mechanism does Ipratropium (Atrovent) use to control broncho-pulmonary diseases?
blocks the action of acetylcholine at parasympathetic sites in bronchial smooth muscle
What major drug interaction does Ipratropium (Atrovent) have?
no major interactions
What is the brand name for Ipratropium?
Atrovent
What type of pulmonary drug is a adrenergic beta-2 agonist, Sympathomimetic drug?
Albuterol (Proventil)
What type of pulmonary complication is Albuterol (Proventil) used to control?
bronchospasm relief in reversible airway diseases
What mechanism does Albuterol (Proventil) use to control broncho-pulmonary diseases?
that stimulates beta-2 adrenergic receptors in the lungs, which results in the relaxation of bronchial smooth muscle
What major drug interaction does Albuterol (Proventil) have?
toxic effect when combined with Fiorcet with codeine
What is the brand name for Albuterol?
Proventil
What type of pulmonary drug is a Long acting selective Beta-2 Adrenergic Agonist?
Salmeterol (Serevant)
What type of pulmonary complication is Salmeterol (Serevant) used to control?
relief of bronchospasms associated with COPD and asthma
What mechanism does Salmeterol (Serevant) use to control broncho-pulmonary diseases?
Adrenergic agonist drug that stimulates beta-2 adrenergic receptors in the lungs, resulting in relaxation of bronchial smooth muscle
What major drug interaction does Salmeterol (Serevant) have?
local anesthetics, antibiotics, antifungals, NSAIDs, Fiorcet with codeine
What is the brand name for Salmeterol?
Serevant
What type of pulmonary drug is a Medium Potency Synthetic Corticosteroid?
Fluticasone (Flovent)
What type of pulmonary complication is Fluticasone (Flovent) used to control?
nasal spray in the management of nasal symptoms of seasonal and perennial allergic and non-allergic rhinitis
What mechanism does Fluticasone (Flovent) use to control broncho-pulmonary diseases?
controls the rate of protein synthesis, depresses migration of PMN leukocytes, reverses capillary permeability, and stabilizes lysosomal membranes.
What major drug interaction does Fluticasone (Flovent) have?
antibiotics, antifungals, antivirals
What is the brand name for Fluticasone?
Flovent
What type of pulmonary drug is a Selective Leukotriene Receptor Antagonist?
Montelukast (Singulair)
What type of pulmonary complication is Montelukast (Singulair) used to control?
asthma and seasonal allergic rhinitis
What mechanism does Montelukast (Singulair) use to control broncho-pulmonary diseases?
binds to receptors decreasing bronchoconstriction, vascular permeability, mucosal edema, and mucus production
What major drug interaction does Montelukast (Singulair) have?
antifungals, antivirals (rifampicin), aspirin percodan
What is the brand name for Montelukast?
Singulair
What type of pulmonary drug is a Xanthine, Theophylline Derivative?
Aminophylline
What type of pulmonary complication is Aminophylline used to control?
bronchial asthma, bronchospasm, and Cheyne-Stokes respirations
What mechanism does Aminophylline use to control broncho-pulmonary diseases?
relieves bronchospasms and increases vital capacity
What major drug interaction does Aminophylline have?
local anesthetics, antibiotics, antifungals, antivirals, Fiorcet with codeine