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Diseases of bones part 3 infection, fractures
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etiology of osteomyelitis is?
pyogenic organisms, mainly staphyloccocus aures
route of infection includes?
hematogenous spread- most common
-direct penetration- less frequent e.g wounds, fractures
Pathology of ostemyelitis:
NE appearance is?
initial suppurative lesion at metaphysis (most vascular part
pathology cont..

1. spread of infection to?
2. ischemic bone necrosis
3. seperation of necrotic bone into ?
4. subperiosteal new bone formation around zone of inflammation called?
1. epiphysis, medullary cavity, cortex of compact bone, rupture into sinus tract of skin
2. incr pressure, isolate more bone from bl supply
3. sequestrum
4. involucrum
clinical feature include?
malaise, fever, chills and leukocytosis
2. bone pain (throbbing pain) usually intense
clinical feature include?
malaise, fever, chills and leukocytosis
2. bone pain (throbbing pain) usually intense
diagnosis of osteomyelitis include?
X-ray
blood culture
biopsy and bone culture
bone scan
MRI
diagnosis of osteomyelitis include?
X-ray
blood culture
biopsy and bone culture
bone scan
MRI
Treatment of osteomyelitis includes?
1. antibiotics (vigorous and prolonged
2. surgery
3. hyperbaric O2 therapy
Treatment of osteomyelitis includes?
1. antibiotics (vigorous and prolonged
2. surgery
3. hyperbaric O2 therapy
Complications of ostemyelitis includes?
1. chronic osteomyelitis
2. pathological fracture
3. direct spread of infection: arthritis
4. blood spread: septicemia
5. secondary amyloidosis
Types of bone fractures are?
1. simple (closed- intact overlying skin
2. compound- (opened): disrupted skin
3. complete-thru bone
4. incomplete- greenstick fracture
5. comminuted: bone breaks 3/more parts
6. traumatic: mechanical injury of norm bone
7. spontaneous: pathological-abn bone ex;tumor
Complications of ostemyelitis includes?
1. chronic osteomyelitis
2. pathological fracture
3. direct spread of infection: arthritis
4. blood spread: septicemia
5. secondary amyloidosis
Types of bone fractures are?
1. simple (closed- intact overlying skin
2. compound- (opened): disrupted skin
3. complete-thru bone
4. incomplete- greenstick fracture
5. comminuted: bone breaks 3/more parts
6. traumatic: mechanical injury of norm bone
7. spontaneous: pathological-abn bone ex;tumor
Healing of fractures include?
1. hematoma- rupt of bl vessel at site of fracture
2. organize of hematoma--procallus
3. diff of local mesenchymal cells into chondroblasts- fibrocartilagenous callus
4. removal internal callus by osteoclasts--leaving intermediate-permanent callus
5. remodeling of permanant callus
a bone that does not heal is called? that may create a false joint or?
1.non union fracture
2. pseudoarthrosis